AZD-1236

DB11961InvestigationalSmall molecule

AZD1236 has been used in trials studying the basic science and treatment of Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.

Mechanism: Pharmacologically active on Matrix metalloproteinase-9 and Macrophage metalloelastase
Curator reviewed
Formula / weight: C₁₅H₁₉ClN₄O₅S · 402.85 g/mol (avg)
Code names: AZD1236

Resolves to

Compound

Structure

InChIKeySFJFBTPHDHUUPU-OAHLLOKOSA-NSMILESC[C@]1(CS(=O)(=O)N2CCC(CC2)OC2=CC=C(Cl)C=N2)NC(=O)NC1=O

Targets

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with AZD-1236, and which of those have an active Phase 3 trial?

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