This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Polihexanide
- DrugBank Accession Number
- DB12277
- Background
Polihexanide has been used in trials studying the treatment, prevention, and supportive care of Caries, Neoplasm, Skin Diseases, Nail Diseases, and Dental Plaque, among others.
- Type
- Small Molecule
- Groups
- Approved, Investigational
- Synonyms
- Polihexanide
- Poly(hexamethylene biguanide)
- Polyhexamethylene biguanide
- Polyhexanide
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Therapies
- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Product Ingredients
Ingredient UNII CAS InChI Key Polihexanide hydrochloride 4XI6112496 32289-58-0 Not applicable - Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Alcohol Free Antibacterial Hand Sanitizer Gel 9 g/10000g Topical Ningbo Meilei Electrical Appliance Co.,LTD 2022-04-18 Not applicable US 
Disinfecting Wet Wipe Cloth 0.9 mg/1 Topical Five Hertz (Xiamen) Medical Supplies Co., Ltd. 2020-03-30 Not applicable US Disposable Disinfectant Spray 0.4 g/100mL Topical Hunan Cihui Medical Technology Co., Ltd. 2020-04-15 Not applicable US Disposable Hand Antibacterial Gel Gel 0.4 g/100mL Topical Biocaro Pharmaceutical Co., Ltd 2020-03-30 Not applicable US HBA Anti bacterial Liquid Spray 0.2 g/100mL Topical Henan Huibo Medical Co., Ltd. 2020-07-22 Not applicable US HBA Sanitary Wipes Solution 5.44 mg/1 Topical Henan Huibo Medical Co., Ltd. 2020-07-22 Not applicable US LeYiJie Alcohol Hand Wash Antibacterial Gel Gel 0.4 g/100mL Topical Biocaro Pharmaceutical Co., Ltd 2020-03-30 Not applicable US PHMB Disinfectant Spray 0.39 mg/1mL Topical Five Hertz (Xiamen) Medical Supplies Co., Ltd. 2020-03-30 Not applicable US PHMB Disinfectant Spray 3.5 g/500mL Extracorporeal Ugel Pharm Tech (Shanghai) Co., Ltd. 2020-05-22 Not applicable US Wash free hand sanitizer(Alcohol free) Solution 1 mg/1mL Topical Shanghai Quanli Daily Necessities Co., Ltd. 2020-03-30 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image (Aenc) Disinfectant WATER-FREE HAND FOAM Polihexanide (0.56 mg/100mL) + Didecyldimethylammonium chloride (0.11 mg/100mL) Solution Topical Yantai Dongke Lvzhiyuan Disinfection Pharmaceutical Co., Ltd. 2020-05-20 2021-11-23 US Cleansing Disinfection Wipes Polihexanide (0.05 1/1001) + Benzalkonium chloride (0.1 1/1001) + Didecyldimethylammonium chloride (0.3 1/1001) + Ethanol (10 1/1001) Cloth Topical Guangdong Bolicen Bio-Technology Co., Ltd. 2020-07-12 Not applicable US COMPLETE MULTI-PURPOSE SOLUTION Polihexanide (0.0001 G/100ML) + Poloxamer 237 (0.05 G/100ML) Solution Ophthalmic บริษัท อลิซไลฟ์ จำกัด จำกัด 2016-12-06 2019-10-21 Thailand 
Ucheer C Polihexanide hydrochloride (0.3 g/100mL) + Benzalkonium chloride (0.3 g/100mL) Liquid Topical Ucheer Purification and Pollution-control Technology(Zhejiang)Co.,Ltd. 2020-04-15 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image (Aenc) Disinfectant WATER-FREE HAND FOAM Polihexanide (0.56 mg/100mL) + Didecyldimethylammonium chloride (0.11 mg/100mL) Solution Topical Yantai Dongke Lvzhiyuan Disinfection Pharmaceutical Co., Ltd. 2020-05-20 2021-11-23 US Alcohol Free Antibacterial Hand Sanitizer Polihexanide (9 g/10000g) Gel Topical Ningbo Meilei Electrical Appliance Co.,LTD 2022-04-18 Not applicable US Disinfecting Wet Wipe Polihexanide (0.9 mg/1) Cloth Topical Five Hertz (Xiamen) Medical Supplies Co., Ltd. 2020-03-30 Not applicable US Disposable Disinfectant Polihexanide (0.4 g/100mL) Spray Topical Hunan Cihui Medical Technology Co., Ltd. 2020-04-15 Not applicable US Disposable Hand Antibacterial Gel Polihexanide (0.4 g/100mL) Gel Topical Biocaro Pharmaceutical Co., Ltd 2020-03-30 Not applicable US HBA Anti bacterial Liquid Polihexanide (0.2 g/100mL) Spray Topical Henan Huibo Medical Co., Ltd. 2020-07-22 Not applicable US HBA Sanitary Wipes Polihexanide (5.44 mg/1) Solution Topical Henan Huibo Medical Co., Ltd. 2020-07-22 Not applicable US LeYiJie Alcohol Hand Wash Antibacterial Gel Polihexanide (0.4 g/100mL) Gel Topical Biocaro Pharmaceutical Co., Ltd 2020-03-30 Not applicable US PHMB Disinfectant Polihexanide (0.39 mg/1mL) Spray Topical Five Hertz (Xiamen) Medical Supplies Co., Ltd. 2020-03-30 Not applicable US PHMB Disinfectant Polihexanide hydrochloride (3.5 g/500mL) Spray Extracorporeal Ugel Pharm Tech (Shanghai) Co., Ltd. 2020-05-22 Not applicable US
Categories
- ATC Codes
- D08AC05 — Polihexanide
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 322U039GMF
- CAS number
- 28757-47-3
References
- General References
- DailyMed: HBA Antibacterial Liquid (polihexanide) topical spray [Link]
- External Links
- PubChem Substance
- 347911310
- 1373041
- Wikipedia
- Polyhexanide
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Completed Prevention Nail Diseases / Nails, Ingrown / Skin Diseases 1 3 Completed Supportive Care Neoplasm / Wounds and Injuries 1 3 Completed Treatment Surgical Site Infections 1 2 Completed Treatment Irreversible Pulpitis (Toothache) 1 1 Completed Treatment Acanthamoeba Keratitis 1 Not Available Completed Prevention Caries / Oral Surgical Wound Infection / Periimplantitis / Periodontal Disease / Plaque, Dental 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Solution Topical Gel Topical 9 g/10000g Cloth Topical Solution Ophthalmic Cloth Topical 0.9 mg/1 Spray Topical 0.4 g/100mL Spray Topical 0.2 g/100mL Solution Topical 5.44 mg/1 Gel Topical 0.4 g/100mL Shampoo Topical 0.8 g Spray Extracorporeal 3.5 g/500mL Spray Topical 0.39 mg/1mL Liquid Topical Solution Topical 1 mg/1mL - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at October 20, 2016 21:48 / Updated at May 09, 2023 23:23