AZD-5423

DB12280InvestigationalSmall molecule

AZD5423 has been used in trials studying the basic science and treatment of Asthma, Bioavailability and AUC, and Chronic Obstructive Pulmonary Disease (COPD).

Mechanism: Pharmacologically active on Glucocorticoid receptor
Curator reviewed
Formula / weight: C₂₅H₂₁F₄N₃O₃ · 487.455 g/mol (avg)
Code names: AZD5423

Resolves to

Compound

UNII641H0Q518WCAS1034148-04-3ChEMBLCHEMBL4072756PubChem24825740

Structure

InChIKeyFCNQMDSJHADDFT-WNSKOXEYSA-NSMILESCOC1=CC(=CC=C1)[C@@H](OC1=CC=C2N(N=CC2=C1)C1=CC=C(F)C=C1)[C@H](C)NC(=O)C(F)(F)F

Targets

P04150NR3C1

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

6Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with AZD-5423, and which of those have an active Phase 3 trial?

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