GLPG-0187

DB12297InvestigationalSmall molecule

GLPG0187 has been used in trials studying the treatment of Solid Tumors.

Mechanism: Pharmacologically active on Integrin beta-1, Integrin alpha-V, and Integrin alpha-5
Curator reviewed
Formula / weight: C₂₉H₃₇N₇O₅S · 595.72 g/mol (avg)
Code names: GLPG0187

Resolves to

Compound

Structure

InChIKeyCXHCNOMGODVIKB-VWLOTQADSA-NSMILESCOC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CNC1=C(C)C(=NC(C)=N1)N1CCC(CC1)C1=CC=C2CCCNC2=N1)C(O)=O

Targets

What you can answer from here — as of July 07, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with GLPG-0187, and which of those have an active Phase 3 trial?

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