Amcipatricin

DB12333InvestigationalSmall molecule

Amcipatricin has been used in trials studying the treatment of Cryptococcosis or Aspergillosis Infections. Amcipatricin (as amcipatricin diascorbate; SPK-843) is a water-soluble partricin derivative patented by SPA Societa Prodotti Antibiotici... In preclinical models, SPK-843 shows in vitro inhibitory activity comparable to or better than that of Amphotericin B against Candida spp., Cryptococcus neoformans, and Aspergillus spp.

Formula / weight: C₆₇H₁₀₃N₅O₁₉ · 1282.577 g/mol (avg)
Code names: SPA-S-752

Resolves to

Compound

UNIIQO0X1DPX2DCAS143483-67-4

Structure

InChIKeyUJGVOBAKMNJQEV-LYLBHANESA-NSMILES

[H][C@]12C[C@@H](O[C@]3([H])O[C@H](C)[C@@H](O)[C@H](NC(=O)CN(C)C)[C@@H]3O)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\[C@H](C)[C@]([H])(OC(=O)C[C@H](O)CC(=O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(=O)NCCN(C)C)O2)[C@@H](C)CCC(O)CC(=O)C1=CC=C(NC)C=C1

What you can answer from here — as of August 30, 2026

1Clinical trialPhase, status and sponsor resolved per trial

Which companies are running trials of Amcipatricin, in which indications and phases, and which of those programs are still active?

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