Siagoside

DB12351InvestigationalSmall molecule

Siagoside (Sygen, AGF 2) has been investigated for the treatment of Parkinson Disease. It is a naturally occurring substance in the nerve cell’s membrane that is thought to play a... Sygen appears to be beneficial in patients with severe spinal cord injury.

Chemical structure of Siagoside
Formula / weight
C73H129N3O30 · 1528.826 g/mol (avg)
Also known as
Ganglioside GM1 lactone

Resolves to

Structure
InChIKeyWVHBJHLTCHODOA-MYYVOHNDSA-NSMILES[H][C@]1(O[C@@]2(C[C@H](O)[C@H]1NC(C)=O)O[C@H]1[C@@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4O)[C@H]3NC(C)=O)[C@@H](CO)O[C@@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](OC[C@H](NC(=O)CCCCCCCCCCCCCCCCC)[C@H](O)\C=C\CCCCCCCCCCCCC)O[C@@H]3CO)[C@@H]1OC2=O)[C@H](O)[C@H](O)CO

What you can answer from here — as of May 14, 2021

1Clinical trialPhase, status and sponsor resolved per trial
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Which companies are running trials of Siagoside, in which indications and phases, and which of those programs are still active?

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