This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Chlorine dioxide
DrugBank Accession Number
DB12453
Background

Chlorine Dioxide has been used in trials studying the treatment of Halitosis.

Type
Small Molecule
Groups
Investigational
Structure
Weight
Average: 67.45
Monoisotopic: 66.9586819
Chemical Formula
ClO2
Synonyms
Not Available

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Air Shield SanitizerStick0.12 g/100gTopicalJS Advisory Co., Ltd2020-12-21Not applicableUS flag
Chlorine Dioxide Air DisinfectantPowder130 mg/6.5gTopicalChengdu Xinyi Kaiwei Medical Equipment Co., Ltd.2020-05-06Not applicableUS flag
Disinfectant and SanitizerTablet, for solution7 g/1001TopicalPUU LIH BIO-TECHNOLOGY CO., LTD.2020-11-11Not applicableUS flag
Dmine Pentose Medi PlusLiquid1 g/100mLTopicalDMINE COSMETIC CO., LTD2020-07-22Not applicableUS flag
Jiajia Gaseous Air DisinfectantSpray32 mg/1gTopicalFujian Meisheng Environmental protection Co.,Ltd2021-10-14Not applicableUS flag
JoydenLiquid0.003 g/100mLTopicalPrivate company NEOCL2020-10-27Not applicableUS flag
JoydenLiquid0.003 g/100mLTopicalPrivate company NEOCL2020-04-11Not applicableUS flag
Joyden plusLiquid0.3 g/100mLTopicalPrivate company NEOCL2020-04-11Not applicableUS flag
Ko-c100Tablet, for solution0.1 g/1gExtracorporealDONG FUH BIOTECH CO., LTD.2021-04-09Not applicableUS flag
M.C. (Morningcalm) V ZeroLiquid0.3 g/100mLTopicalMorningcalmsalt Co., Ltd.2020-10-07Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Ecopp Portable Virus ProectionChlorine dioxide (0.595 g/3.5g) + Ammonium chloride (0.007 g/3.5g)GranuleExtracorporealShenzhen Econin Environmental Protection Technology Co., Ltd.2020-03-28Not applicableUS flag
Guardian AngelChlorine dioxide (5 mg/1) + Water (2 L/1)LiquidTopicalBTC TOP, INC2020-08-25Not applicableUS flag
Ontree LifeChlorine dioxide (0.02 g/100mL) + Titanium dioxide (0.05 g/100mL)LiquidTopicalO22020-09-04Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Air Shield SanitizerChlorine dioxide (0.12 g/100g)StickTopicalJS Advisory Co., Ltd2020-12-21Not applicableUS flag
Chlorine Dioxide Air DisinfectantChlorine dioxide (130 mg/6.5g)PowderTopicalChengdu Xinyi Kaiwei Medical Equipment Co., Ltd.2020-05-06Not applicableUS flag
Disinfectant and SanitizerChlorine dioxide (7 g/1001)Tablet, for solutionTopicalPUU LIH BIO-TECHNOLOGY CO., LTD.2020-11-11Not applicableUS flag
Dmine Pentose Medi PlusChlorine dioxide (1 g/100mL)LiquidTopicalDMINE COSMETIC CO., LTD2020-07-22Not applicableUS flag
Ecopp Portable Virus ProectionChlorine dioxide (0.595 g/3.5g) + Ammonium chloride (0.007 g/3.5g)GranuleExtracorporealShenzhen Econin Environmental Protection Technology Co., Ltd.2020-03-28Not applicableUS flag
Jiajia Gaseous Air DisinfectantChlorine dioxide (32 mg/1g)SprayTopicalFujian Meisheng Environmental protection Co.,Ltd2021-10-14Not applicableUS flag
JoydenChlorine dioxide (0.003 g/100mL)LiquidTopicalPrivate company NEOCL2020-04-11Not applicableUS flag
JoydenChlorine dioxide (0.003 g/100mL)LiquidTopicalPrivate company NEOCL2020-10-27Not applicableUS flag
Joyden plusChlorine dioxide (0.3 g/100mL)LiquidTopicalPrivate company NEOCL2020-04-11Not applicableUS flag
Ko-c100Chlorine dioxide (0.1 g/1g)Tablet, for solutionExtracorporealDONG FUH BIOTECH CO., LTD.2021-04-09Not applicableUS flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as non-metal chlorites. These are inorganic non-metallic compounds containing a chlorite as its largest oxoanion.
Kingdom
Inorganic compounds
Super Class
Homogeneous non-metal compounds
Class
Non-metal oxoanionic compounds
Sub Class
Non-metal chlorites
Direct Parent
Non-metal chlorites
Alternative Parents
Inorganic oxides
Substituents
Inorganic oxide / Non-metal chlorite
Molecular Framework
Not Available
External Descriptors
chlorine dioxide (CHEBI:29415)
Affected organisms
Not Available

Chemical Identifiers

UNII
8061YMS4RM
CAS number
10049-04-4
InChI Key
OSVXSBDYLRYLIG-UHFFFAOYSA-N
InChI
InChI=1S/ClO2/c2-1-3
IUPAC Name
chloryl
SMILES
O=[Cl]=O

References

General References
Not Available
Human Metabolome Database
HMDB0034826
PubChem Compound
24870
PubChem Substance
347828694
ChemSpider
23251
RxNav
20799
ChEBI
29415
Wikipedia
Chlorine_dioxide

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedPreventionCaries / Gingival Diseases1
4CompletedPreventionOral Malodor (Halitosis)1
4CompletedTreatmentPeri-implant Mucositis1
2RecruitingSupportive CareCoronavirus Disease 2019 (COVID‑19) / Infections, Coronavirus / Pharyngeal Diseases / Severe Acute Respiratory Syndrome Coronavirus 2 / Virus Diseases1
2SuspendedSupportive CareHead and Neck Carcinoma1
0CompletedTreatmentWound - in Medical Care1
Not AvailableCompletedTreatmentOral Malodor (Halitosis)1
Not AvailableRecruitingNot AvailableCoronavirus Disease 2019 (COVID‑19)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
StickTopical0.12 g/100g
PowderTopical130 mg/6.5g
Tablet, for solutionTopical7 g/1001
LiquidTopical1 g/100mL
GranuleExtracorporeal
LiquidTopical
SprayTopical32 mg/1g
LiquidTopical0.003 g/100mL
LiquidTopical0.3 g/100mL
Tablet, for solutionExtracorporeal0.1 g/1g
LiquidExtracorporeal0.115 mg/500mL
SprayTopical0.05 g/500mL
LiquidTopical0.005 g/100mL
SprayTopical0.003 g/20000mL
LiquidTopical0.01 g/100mL
Granule, delayed releaseExtracorporeal1 g/10g
SprayTopical0.015 g/300mL
LiquidTopical0.02 g/100mL
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility672.0 mg/mLALOGPS
logP-1.3ALOGPS
logP0.26ChemAxon
logS0.99ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area34.14 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity9.02 m3·mol-1ChemAxon
Polarizability3.79 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at October 20, 2016 22:27 / Updated at October 16, 2020 03:34