This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Chlorine dioxide
- DrugBank Accession Number
- DB12453
- Background
Chlorine Dioxide has been used in trials studying the treatment of Halitosis.
- Type
- Small Molecule
- Groups
- Investigational
- Structure
Structure for Chlorine dioxide (DB12453)
- Weight
- Average: 67.45
Monoisotopic: 66.9586819 - Chemical Formula
- ClO2
- Synonyms
- Not Available
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Air Shield Sanitizer Stick 0.12 g/100g Topical JS Advisory Co., Ltd 2020-12-21 2022-11-09 US 
Chlorine Dioxide Air Disinfectant Powder 130 mg/6.5g Topical Chengdu Xinyi Kaiwei Medical Equipment Co., Ltd. 2020-05-06 Not applicable US Disinfectant and Sanitizer Tablet, for solution 7 g/1001 Topical PUU LIH BIO-TECHNOLOGY CO., LTD. 2020-11-11 Not applicable US Dmine Pentose Medi Plus Liquid 1 g/100mL Topical DMINE COSMETIC CO., LTD 2020-07-22 Not applicable US Jiajia Gaseous Air Disinfectant Spray 32 mg/1g Topical Fujian Meisheng Environmental protection Co.,Ltd 2021-10-14 Not applicable US Joyden Liquid 0.003 g/100mL Topical Private company NEOCL 2020-10-27 Not applicable US Joyden Liquid 0.003 g/100mL Topical Private company NEOCL 2020-04-11 Not applicable US Joyden plus Liquid 0.3 g/100mL Topical Private company NEOCL 2020-04-11 Not applicable US Ko-c100 Tablet, for solution 0.1 g/1g Extracorporeal DONG FUH BIOTECH CO., LTD. 2021-04-09 Not applicable US M.C. (Morningcalm) V Zero Liquid 0.3 g/100mL Topical Morningcalmsalt Co., Ltd. 2020-10-07 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Ecopp Portable Virus Proection Chlorine dioxide (0.595 g/3.5g) + Ammonium chloride (0.007 g/3.5g) Granule Extracorporeal Shenzhen Econin Environmental Protection Technology Co., Ltd. 2020-03-28 Not applicable US Guardian Angel Chlorine dioxide (5 mg/1) + Water (2 L/1) Liquid Topical BTC TOP, INC 2020-08-25 Not applicable US Ontree Life Chlorine dioxide (0.02 g/100mL) + Titanium dioxide (0.05 g/100mL) Liquid Topical O2 2020-09-04 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Air Shield Sanitizer Chlorine dioxide (0.12 g/100g) Stick Topical JS Advisory Co., Ltd 2020-12-21 2022-11-09 US Chlorine Dioxide Air Disinfectant Chlorine dioxide (130 mg/6.5g) Powder Topical Chengdu Xinyi Kaiwei Medical Equipment Co., Ltd. 2020-05-06 Not applicable US Disinfectant and Sanitizer Chlorine dioxide (7 g/1001) Tablet, for solution Topical PUU LIH BIO-TECHNOLOGY CO., LTD. 2020-11-11 Not applicable US Dmine Pentose Medi Plus Chlorine dioxide (1 g/100mL) Liquid Topical DMINE COSMETIC CO., LTD 2020-07-22 Not applicable US Ecopp Portable Virus Proection Chlorine dioxide (0.595 g/3.5g) + Ammonium chloride (0.007 g/3.5g) Granule Extracorporeal Shenzhen Econin Environmental Protection Technology Co., Ltd. 2020-03-28 Not applicable US Jiajia Gaseous Air Disinfectant Chlorine dioxide (32 mg/1g) Spray Topical Fujian Meisheng Environmental protection Co.,Ltd 2021-10-14 Not applicable US Joyden Chlorine dioxide (0.003 g/100mL) Liquid Topical Private company NEOCL 2020-04-11 Not applicable US Joyden Chlorine dioxide (0.003 g/100mL) Liquid Topical Private company NEOCL 2020-10-27 Not applicable US Joyden plus Chlorine dioxide (0.3 g/100mL) Liquid Topical Private company NEOCL 2020-04-11 Not applicable US Ko-c100 Chlorine dioxide (0.1 g/1g) Tablet, for solution Extracorporeal DONG FUH BIOTECH CO., LTD. 2021-04-09 Not applicable US
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of inorganic compounds known as non-metal chlorites. These are inorganic non-metallic compounds containing a chlorite as its largest oxoanion.
- Kingdom
- Inorganic compounds
- Super Class
- Homogeneous non-metal compounds
- Class
- Non-metal oxoanionic compounds
- Sub Class
- Non-metal chlorites
- Direct Parent
- Non-metal chlorites
- Alternative Parents
- Inorganic oxides
- Substituents
- Inorganic oxide / Non-metal chlorite
- Molecular Framework
- Not Available
- External Descriptors
- chlorine dioxide (CHEBI:29415)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 8061YMS4RM
- CAS number
- 10049-04-4
- InChI Key
- OSVXSBDYLRYLIG-UHFFFAOYSA-N
- InChI
- InChI=1S/ClO2/c2-1-3
- IUPAC Name
- chloryl
- SMILES
- O=[Cl]=O
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0034826
- PubChem Compound
- 24870
- PubChem Substance
- 347828694
- ChemSpider
- 23251
- 20799
- ChEBI
- 29415
- Wikipedia
- Chlorine_dioxide
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Completed Prevention Caries / Gingival Diseases 1 4 Completed Prevention Oral Malodor (Halitosis) 1 4 Completed Treatment Peri-implant Mucositis 1 2 Completed Supportive Care Coronavirus Disease 2019 (COVID‑19) / Infections, Coronavirus / Pharyngeal Diseases / Severe Acute Respiratory Syndrome Coronavirus 2 / Viral Disease 1 2 Suspended Supportive Care Carcinoma of the Head and Neck 1 0 Completed Treatment Wound - in Medical Care 1 Not Available Completed Treatment Oral Malodor (Halitosis) 1 Not Available Unknown Status Not Available Coronavirus Disease 2019 (COVID‑19) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Stick Topical 0.12 g/100g Powder Topical 130 mg/6.5g Tablet, for solution Topical 7 g/1001 Liquid Topical 1 g/100mL Granule Extracorporeal Liquid Topical Spray Topical 32 mg/1g Liquid Topical 0.003 g/100mL Liquid Topical 0.3 g/100mL Tablet, for solution Extracorporeal 0.1 g/1g Liquid Extracorporeal 0.115 mg/500mL Spray Topical 0.05 g/500mL Liquid Topical 0.005 g/100mL Spray Topical 0.003 g/20000mL Liquid Topical 0.01 g/100mL Granule, delayed release Extracorporeal 1 g/10g Spray Topical 0.015 g/300mL Liquid Topical 0.02 g/100mL - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 672.0 mg/mL ALOGPS logP -1.3 ALOGPS logP 0.26 Chemaxon logS 0.99 ALOGPS Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 34.14 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 9.02 m3·mol-1 Chemaxon Polarizability 3.79 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at October 20, 2016 22:27 / Updated at October 16, 2020 03:34