Semagacestat

DB12463InvestigationalSmall molecule

Semagacestat has been used in trials studying the treatment of Alzheimer Disease.

Chemical structure of Semagacestat
Formula / weight
C19H27N3O4 · 361.442 g/mol (avg)
Code names
LY-450139

Resolves to

Compound
UNII3YN0602W4WCAS425386-60-3ChEMBLCHEMBL520733ChEBI131158PubChem9843750
Structure
InChIKeyPKXWXXPNHIWQHW-RCBQFDQVSA-NSMILESCC(C)[C@H](O)C(=O)N[C@@H](C)C(=O)N[C@H]1C2=CC=CC=C2CCN(C)C1=O
Targets
P49768PSEN1Q92542NCSTNQ9NZ42PSENENQ8WW43APH1BQ96BI3APH1A

What you can answer from here — as of January 29, 2025

5Protein targetsEach mapped to UniProt, with action and pharmacological action
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3Clinical trialsPhase, status and sponsor resolved per trial
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5+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Semagacestat, and which of those have an active Phase 3 trial?

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