ABT-384

DB12501InvestigationalSmall molecule

ABT-384 has been used in trials studying the treatment of Alzheimer's Disease.

Mechanism: Pharmacologically active on 11-beta-hydroxysteroid dehydrogenase 1
Curator reviewed
Formula / weight: C₂₅H₃₄F₃N₅O₂ · 493.575 g/mol (avg)
Code names: ABT-384

Resolves to

Compound

Structure

InChIKeyCLHMYBJIOZXCEX-MALZWFGSSA-NSMILESCC(C)(N1CCN(CC1)C1=NC=C(C=C1)C(F)(F)F)C(=O)N[C@H]1C2CC3CC1C[C@@](C3)(C2)C(N)=O

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with ABT-384, and which of those have an active Phase 3 trial?

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