Edicotinib

DB12504InvestigationalSmall molecule

JNJ-40346527 has been used in trials studying the treatment of Health and Arthritis, Rheumatoid.

Mechanism: Pharmacologically active on Macrophage colony-stimulating factor 1 receptor
Curator reviewed
Formula / weight: C₂₇H₃₅N₅O₂ · 461.61 g/mol (avg)
Code names: JNJ-40346527

Resolves to

Compound

Structure

InChIKeyBNVPFDRNGHMRJS-UHFFFAOYSA-NSMILESCC1(C)CCC(=CC1)C1=C(NC(=O)C2=NC=C(N2)C#N)C=CC(=N1)C1CC(C)(C)OC(C)(C)C1

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

5Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Edicotinib, and which of those have an active Phase 3 trial?

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