ATX-914

DB12673InvestigationalSmall molecule

Axt914 is under investigation in clinical trial NCT00417261 (Safety, Tolerability, Pharmacodynamic and Pharmacokinetic Effects of Single and Multiple-Doses of ATF936 and AXT914 Administered Orally in Healthy Subjects.).

Mechanism: Pharmacologically active on Extracellular calcium-sensing receptor
Curator reviewed
Formula / weight: C₂₉H₂₃BrN₄O₂ · 539.433 g/mol (avg)
Code names: AXT914

Resolves to

Compound

UNII8VK61D7U5DPubChem119026214

Structure

InChIKeyALANRBCCCQEPFZ-UHFFFAOYSA-NSMILESCC(C)C1=CC=C(C=C1)C1=NC(=O)N(CC2=CC=C3N=C(Br)C=NC3=C2)C2=CC=C(OCC#C)C=C12

Targets

P41180CASR

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with ATX-914, and which of those have an active Phase 3 trial?

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