GW-493838

DB12760InvestigationalSmall molecule

GW493838 has been used in trials studying the treatment of Neuropathic Pain.

Mechanism: Pharmacologically active on Adenosine receptor A1
Curator reviewed
Formula / weight: C₂₁H₂₁ClFN₇O₄ · 489.89 g/mol (avg)
Code names: 493838 · GW493838 · GW-493838 X

Resolves to

Compound

Structure

InChIKeyZQYJPMPXQLNTPQ-QCUYGVNKSA-NSMILESCC(C)(C)C1=NN=C(O1)[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(NC3=CC=C(Cl)C=C3F)N=CN=C12

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with GW-493838, and which of those have an active Phase 3 trial?

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