Rivipansel

DB12778InvestigationalSmall molecule

Rivipansel has been used in trials studying the other, basic science, and treatment of Pain Crisis, Renal impairment, Anemia, Sickle Cell, Sickle Cell Disease, and Sickle Cell Disorders, among others.

Mechanism: Pharmacologically active on P-selectin, L-selectin, and E-selectin
Curator reviewed
Formula / weight: C₅₈H₇₄N₆O₃₁S₃ · 1447.42 g/mol (avg)
Also known as: GMI-1070
Code names: PF-06460031

Resolves to

Compound

UNII4B115V09LBCAS927881-99-0ChEMBLCHEMBL3707446

Structure

InChIKeyVXBNTHRZPJLRSS-PTCSXESPSA-NSMILES

[H][C@@](CC1CCCCC1)(O[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](O[C@@H]2C[C@@H](C[C@H](NC(=O)C3=CC(=O)NC(=O)N3)[C@H]2O[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)C(=O)NCCNC(=O)COCCOCC(=O)NC2=C3C(=CC(=C2)S(O)(=O)=O)C=C(C=C3S(O)(=O)=O)S(O)(=O)=O)[C@@H]1OC(=O)C1=CC=CC=C1)C(O)=O

Targets

P16109SELPP14151SELLP16581SELE

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

8Clinical trialsPhase, status and sponsor resolved per trial

9+ReferencesStructured and connected to the statements they support

Which drugs share a target with Rivipansel, and which of those have an active Phase 3 trial?

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