Pradigastat

DB12866InvestigationalSmall molecule

Pradigastat has been used in trials studying the treatment of Non-alcoholic Fatty Liver Disease (NAFLD).

Mechanism: Pharmacologically active on Diacylglycerol O-acyltransferase 1
Curator reviewed
Formula / weight: C₂₅H₂₄F₃N₃O₂ · 455.481 g/mol (avg)
Code names: LCQ-908 · LCQ-908NXA

Resolves to

Compound

Structure

InChIKeyGXALXAKNHIROPE-QAQDUYKDSA-NSMILESOC(=O)C[C@H]1CC[C@@H](CC1)C1=CC=C(C=C1)C1=NC=C(NC2=CN=C(C=C2)C(F)(F)F)C=C1

Targets

Transporters

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1TransporterSubstrate / inhibitor direction, not just membership

Listed above

69Drug interactionsStructured to mechanism, not free text

10Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Pradigastat, and which of those have an active Phase 3 trial?

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