RO-4987655

DB12933InvestigationalSmall molecule

RO4987655 has been used in trials studying the treatment of Neoplasms.

Mechanism: Pharmacologically active on Dual specificity mitogen-activated protein kinase kinase 1, Dual specificity mitogen-activated protein kinase kinase 2, and Mitogen-activated protein kinase kinase (MAPKK)
Curator reviewed
Formula / weight: C₂₀H₁₉F₃IN₃O₅ · 565.2816 g/mol (avg)
Code names: CH-4987655 · RG-7167 · RO-4987655

Resolves to

Compound

Structure

InChIKeyFIMYFEGKMOCQKT-UHFFFAOYSA-NSMILESOCCONC(=O)C1=CC(CN2OCCCC2=O)=C(F)C(F)=C1NC1=CC=C(I)C=C1F

Targets

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

10+ReferencesStructured and connected to the statements they support

Which drugs share a target with RO-4987655, and which of those have an active Phase 3 trial?

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