Pyronaridine

DB12975InvestigationalSmall molecule

Pyronaridine is a benzonaphthyridine derivative indicated in the treatment of acute malaria caused by P. falciparum or P. vivax in area with low rates of infection and low resistance to artemisinin. A medication used to treat malaria.

Mechanism: Pharmacologically active on Fe(II)-protoporphyrin IX
Curator reviewed
Formula / weight: C₂₉H₃₂ClN₅O₂ · 518.06 g/mol (avg)

Resolves to

Compound

UNIITD3P7Q3SG6CAS74847-35-1ChEMBLCHEMBL35228ChEBI135951PubChem107771

Clinical / RWD

ATCP01BF06

Structure

InChIKeyDJUFPMUQJKWIJB-UHFFFAOYSA-NSMILESCOC1=NC2=C(NC3=CC(CN4CCCC4)=C(O)C(CN4CCCC4)=C3)C3=CC=C(Cl)C=C3N=C2C=C1

Targets

O15245SLC22A1

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

68Drug interactionsStructured to mechanism, not free text

30Clinical trialsPhase, status and sponsor resolved per trial

2Structured indicationsCondition, population, route and combination as fields, not prose

1Marketed productAcross 1 country and 1 labeller

1ATC codeIncluding every combination product, plus 7 drug categories

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Pyronaridine, and which of those have an active Phase 3 trial?

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