Pyronaridine

DB12975InvestigationalSmall molecule

Pyronaridine is a benzonaphthyridine derivative indicated in the treatment of acute malaria caused by P. falciparum or P. vivax in area with low rates of infection and low resistance to artemisinin. A medication used to treat malaria.

Mechanism: Pharmacologically active on Fe(II)-protoporphyrin IX
Curator reviewed
Formula / weight: C₂₉H₃₂ClN₅O₂ · 518.06 g/mol (avg)

Resolves to

Compound

UNIITD3P7Q3SG6CAS74847-35-1ChEMBLCHEMBL35228ChEBI135951PubChem5485198

Clinical / RWD

ATCP01BF06

Structure

InChIKeyDJUFPMUQJKWIJB-UHFFFAOYSA-NSMILESCOC1=NC2=C(NC3=CC(CN4CCCC4)=C(O)C(CN4CCCC4)=C3)C3=CC=C(Cl)C=C3N=C2C=C1

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

68Drug interactionsStructured to mechanism, not free text

30Clinical trialsPhase, status and sponsor resolved per trial

2Structured indicationsCondition, population, route and combination as fields, not prose

1Marketed productAcross 1 country and 1 labeller

1ATC codeIncluding every combination product, plus 6 drug categories

3+ReferencesStructured and connected to the statements they support

Which other approved drugs treat the same conditions as Pyronaridine, and which companies have late-stage candidates in those indications?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account