Simenepag isopropyl

DB12977InvestigationalSmall molecule

Simenepag isopropyl has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.

Chemical structure of Simenepag isopropyl
Mechanism
Curator reviewed
Formula / weight
C26H35NO5S · 473.63 g/mol (avg)
Code names
AGN-210669

Resolves to

Compound
UNII8908HU0G4KCAS910562-13-9ChEMBLCHEMBL2105710PubChem46902081
Structure
InChIKeyMSIIJNOQQWRTFC-GGAORHGYSA-NSMILESCCCCC[C@H](O)C1=CC=C(C=C1)N1[C@@H](COCC2=CC=C(S2)C(=O)OC(C)C)CCC1=O
Targets
P43116PTGER2

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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2Clinical trialsPhase, status and sponsor resolved per trial
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Simenepag isopropyl, and which of those have an active Phase 3 trial?

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