Bleomycin A6

DB12992InvestigationalSmall molecule

Bleomycin A6 (also known as boanmycin) has been used in trials studying the treatment of Squamous Cell Lung Cancer. It was developed in China as an antineoplastic antibiotic. This drug... It was shown that besides the antitumor effect, Bleomycin A6 had the ability to alter the tumor microenvironment and could contribute toward lung cancer relapse and metastasis on long-term treatment.

Chemical structure of Bleomycin A6
Formula / weight
C60H96N20O21S2 · 1497.67 g/mol (avg)
Also known as
Boanmycin · Pingyangmycin A6 · Zhengguangmycin A6

Resolves to

Structure
InChIKeyFOUFFVYWFNBHHH-YNGSZULRSA-NSMILES[H][C@]1(O[C@H]2[C@@H](O)[C@H](O)[C@H](CO)O[C@H]2O[C@H]([C@H](NC(=O)C2=NC(=NC(N)=C2C)[C@H](CC(N)=O)NC[C@H](N)C(N)=O)C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCCC2=NC(=CS2)C2=NC(=CS2)C(=O)NCCCNCCCCNCCCN)C2=CN=CN2)O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O

What you can answer from here — as of April 02, 2025

1Clinical trialPhase, status and sponsor resolved per trial
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Which companies are running trials of Bleomycin A6, in which indications and phases, and which of those programs are still active?

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