PCI-27483

DB13000InvestigationalSmall molecule

PCI-27483 has been used in trials studying the treatment of Pancreatic Cancer, Ductal Adrenocarcinoma, and Exocrine Pancreatic Cancer.

Mechanism: Pharmacologically active on Coagulation factor VII
Curator reviewed
Formula / weight: C₂₆H₂₄N₆O₉S · 596.57 g/mol (avg)
Code names: PCI-27483

Resolves to

Compound

Structure

InChIKeyWDJHHCAKBRKCLW-IBGZPJMESA-NSMILESNC(=N)C1=CC=C2N=C(NC2=C1)C1=CC(CC(=O)N[C@@H](CC(O)=O)C(O)=O)=CC(=C1O)C1=CC(=CC=C1O)S(N)(=O)=O

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with PCI-27483, and which of those have an active Phase 3 trial?

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