ACT-451840

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DB13054InvestigationalSmall molecule

ACT-451840 has been used in trials studying Malaria.

Formula / weight: C₄₇H₅₄N₆O₃ · 750.988 g/mol (avg)
Code names: ACT-451840

Resolves to

Compound

UNIIFO890BDO84CAS1839508-99-4PubChem53303762

Structure

InChIKeyBQZUYCCCNXOADJ-TVNMEPFQSA-NSMILESCC(=O)N1CCN(CC1)C1=CC=C(CN([C@@H](CC2=CC=CC=C2)C(=O)N2CCN(CC3=CC=C(C=C3)C#N)CC2)C(=O)\C=C\C2=CC=C(C=C2)C(C)(C)C)C=C1

Targets

P13568MDR1

Transporters

P13568MDR1

What you can answer from here — as of August 14, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1TransporterSubstrate / inhibitor direction, not just membership

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with ACT-451840, and which of those have an active Phase 3 trial?

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