Rotigaptide

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DB13067InvestigationalSmall molecule

Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease.

Mechanism: Pharmacologically active on Gap junction alpha-1 protein
Curator reviewed
Formula / weight: C₂₈H₃₉N₇O₉ · 617.66 g/mol (avg)

Resolves to

Compound

UNIIGFA1W6KO7NCAS355151-12-1ChEMBLCHEMBL450656PubChem9938933

Structure

InChIKeyGFJRASPBQLDRRY-TWTQBQJDSA-NSMILESC[C@@H](NC(=O)CNC(=O)[C@H]1C[C@H](O)CN1C(=O)[C@H]1CCCN1C(=O)[C@@H](CC1=CC=C(O)C=C1)NC(C)=O)C(=O)NCC(N)=O

Targets

P17302GJA1P0DTD1rep

What you can answer from here — as of July 07, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Rotigaptide, and which of those have an active Phase 3 trial?

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