Delpazolid

DB13077InvestigationalSmall molecule

Delpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).

Mechanism: Pharmacologically active on 23S ribosomal RNA
Curator reviewed
Formula / weight: C₁₄H₁₇FN₄O₃ · 308.313 g/mol (avg)
Also known as: (5R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one · (5R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one · (R)-3-[3-Fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2,4-triazin-4-yl)phenyl]-5(R)-(hydroxymethyl)oxazolidin-2-one · 2-oxazolidinone, 3-(4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl)-5-(hydroxymethyl)-, (5R)-
Code names: LCB-01-0371

Resolves to

Compound

UNII43EP6XV33ECAS1219707-39-7ChEMBLCHEMBL1673408PubChem44205191

Structure

InChIKeyQLUWQAFDTNAYPN-LLVKDONJSA-NSMILESCN1CCN(C=N1)C1=CC=C(C=C1F)N1C[C@H](CO)OC1=O

What you can answer from here — as of July 29, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

56Drug interactionsStructured to mechanism, not free text

9Clinical trialsPhase, status and sponsor resolved per trial

7+ReferencesStructured and connected to the statements they support

Which companies are running trials of Delpazolid, in which indications and phases, and which of those programs are still active?

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