Ethacridine

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Ethacridine
DrugBank Accession Number
DB13190
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 253.305
Monoisotopic: 253.121512115
Chemical Formula
C15H15N3O
Synonyms
  • Etacridina
  • Ethacridine
  • Ethacridinum

Pharmacology

Indication

Not Available

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Associated Therapies
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Ethacridine lactate7T7T2I98231837-57-6IYLLULUTZPKQBW-UHFFFAOYSA-N
Ethacridine lactate monohydrateV5IL571C1T6402-23-9NYEPHMYJRNWPLA-UHFFFAOYSA-N
International/Other Brands
Rivanol

Categories

ATC Codes
D08AA01 — Ethacridine lactateB05CA08 — Ethacridine lactate
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as acridines. These are organic compounds containing the acridine moiety, a linear tricyclic heterocycle which consists of two benzene rings joined by a pyridine ring.
Kingdom
Organic compounds
Super Class
Organoheterocyclic compounds
Class
Quinolines and derivatives
Sub Class
Benzoquinolines
Direct Parent
Acridines
Alternative Parents
4-aminoquinolines / Aminopyridines and derivatives / Alkyl aryl ethers / Benzenoids / Heteroaromatic compounds / Azacyclic compounds / Primary amines / Organopnictogen compounds / Hydrocarbon derivatives
Substituents
4-aminoquinoline / Acridine / Alkyl aryl ether / Amine / Aminopyridine / Aminoquinoline / Aromatic heteropolycyclic compound / Azacycle / Benzenoid / Ether
Molecular Framework
Aromatic heteropolycyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
WIX85M1A6R
CAS number
442-16-0
InChI Key
CIKWKGFPFXJVGW-UHFFFAOYSA-N
InChI
InChI=1S/C15H15N3O/c1-2-19-10-4-6-13-12(8-10)15(17)11-5-3-9(16)7-14(11)18-13/h3-8H,2,16H2,1H3,(H2,17,18)
IUPAC Name
7-ethoxy-9-imino-9,10-dihydroacridin-3-amine
SMILES
CCOC1=CC2=C(NC3=C(C=CC(N)=C3)C2=N)C=C1

References

General References
  1. Likuid Pharmalab Indonesia: Rivanol (ethacridine lactate) product information [Link]
ChemSpider
1940
BindingDB
24709
RxNav
4106
ChEBI
135032
ChEMBL
CHEMBL94007
ZINC
ZINC000018107429
Wikipedia
Ethacridine_lactate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionTopical
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.192 mg/mLALOGPS
logP2.59ALOGPS
logP2.28Chemaxon
logS-3.1ALOGPS
pKa (Strongest Acidic)18.09Chemaxon
pKa (Strongest Basic)12.12Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count3Chemaxon
Polar Surface Area71.13 Å2Chemaxon
Rotatable Bond Count2Chemaxon
Refractivity87.45 m3·mol-1Chemaxon
Polarizability28.25 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSsplash10-004j-0590000000-22b194e7a280cdce629c
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0udi-0090000000-c15105de67cc73be7a37
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-0090000000-17387411bb40066833c1
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0udi-0090000000-95817dc9ce1ea56858c0
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0fk9-0090000000-e92a1ac7940b2cf11895
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4j-0890000000-12a4fa0bfd10a3de365c
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-00di-0490000000-23d45f4f6a6694bd81cf
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-165.57982
predicted
DeepCCS 1.0 (2019)
[M+H]+167.93784
predicted
DeepCCS 1.0 (2019)
[M+Na]+174.03098
predicted
DeepCCS 1.0 (2019)

Drug created at June 16, 2017 21:38 / Updated at March 18, 2024 16:24