NAV

Sulfadicramide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Sulfadicramide
DrugBank Accession Number
DB13214
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
3D
Similar Structures
Weight
Average: 254.3
Monoisotopic: 254.072513493
Chemical Formula
C11H14N2O3S
Synonyms
  • Sulfadicramide
  • Sulfadicrolamide
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
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AcarboseThe therapeutic efficacy of Acarbose can be increased when used in combination with Sulfadicramide.
AcetohexamideThe therapeutic efficacy of Acetohexamide can be increased when used in combination with Sulfadicramide.
AlbiglutideThe therapeutic efficacy of Albiglutide can be increased when used in combination with Sulfadicramide.
AlogliptinThe therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfadicramide.
BenzylpenicillinSulfadicramide may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level.
Food Interactions
Not Available

Categories

ATC Codes
S01AB03 — Sulfadicramide
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Benzenesulfonamides
Direct Parent
Aminobenzenesulfonamides
Alternative Parents
Benzenesulfonyl compounds / Aniline and substituted anilines / Organosulfonic acids and derivatives / Aminosulfonyl compounds / Amino acids and derivatives / Primary amines / Organopnictogen compounds / Organic oxides / Hydrocarbon derivatives / Carbonyl compounds
Substituents
Amine / Amino acid or derivatives / Aminobenzenesulfonamide / Aminosulfonyl compound / Aniline or substituted anilines / Aromatic homomonocyclic compound / Benzenesulfonyl group / Carbonyl group / Carboxylic acid derivative / Hydrocarbon derivative
Molecular Framework
Aromatic homomonocyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
7WZ5EG263C
CAS number
115-68-4
InChI Key
XRVJPLDTMUSSDE-UHFFFAOYSA-N
InChI
InChI=1S/C11H14N2O3S/c1-8(2)7-11(14)13-17(15,16)10-5-3-9(12)4-6-10/h3-7H,12H2,1-2H3,(H,13,14)
IUPAC Name
N-(4-aminobenzenesulfonyl)-3-methylbut-2-enamide
SMILES
CC(C)=CC(=O)NS(=O)(=O)C1=CC=C(N)C=C1

References

General References
Not Available
ChemSpider
7980
ChEBI
135039
ChEMBL
CHEMBL2104910
ZINC
ZINC000000002093
Wikipedia
Sulfadicramide

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility1.23 mg/mLALOGPS
logP0.63ALOGPS
logP1.13Chemaxon
logS-2.3ALOGPS
pKa (Strongest Acidic)4.41Chemaxon
pKa (Strongest Basic)2.11Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area89.26 Å2Chemaxon
Rotatable Bond Count2Chemaxon
Refractivity67.09 m3·mol-1Chemaxon
Polarizability26.12 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSsplash10-053r-9110000000-0154a31c06d77e8545b9
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4i-0900000000-b8b6c5cba4d0ee5206b8
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-0290000000-a36e524c1c79c4942a11
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0h90-0790000000-de96772f750161d7a379
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4l-7900000000-7dda0b90398265dcf65a
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-014l-9000000000-753c94cb136558db6e49
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-000x-9200000000-bb1e1d2402a55a51fa23
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-167.9012773
predicted
DarkChem Lite v0.1.0
[M-H]-156.75209
predicted
DeepCCS 1.0 (2019)
[M+H]+168.8413773
predicted
DarkChem Lite v0.1.0
[M+H]+159.14766
predicted
DeepCCS 1.0 (2019)
[M+Na]+165.14247
predicted
DeepCCS 1.0 (2019)

Drug created at June 23, 2017 20:37 / Updated at February 21, 2021 18:54