This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Euflavine is a topical disinfectant indicated in the treatment of wounds, blisters, insect bites, and infected wounds.
- Generic Name
- Euflavine
- DrugBank Accession Number
- DB13326
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Euflavine (DB13326)
- Weight
- Average: 259.74
Monoisotopic: 259.0876252 - Chemical Formula
- C14H14ClN3
- Synonyms
- 3,6-diamino-10-methylacridinium chloride
Pharmacology
- Indication
Not Available
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Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination to treat Burns Combination Product in combination with: Thymol (DB02513) ••• ••• •••••• •••••••• Used in combination to treat Insect bites Combination Product in combination with: Thymol (DB02513) ••• ••• •••••• •••••••• Used in combination to treat Purulent wounds caused by infection Combination Product in combination with: Thymol (DB02513) ••• ••• •••••• •••••••• Used in combination to treat Scald burn injuries Combination Product in combination with: Thymol (DB02513) ••• ••• •••••• •••••••• Used in combination to treat Wounds Combination Product in combination with: Thymol (DB02513) ••• ••• •••••• •••••••• - Associated Therapies
- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image โคแนล Cream 0.1 %w/w บริษัท วี แอนด์ พี ลาบอราตอรี่ จำกัด จำกัด 1989-07-27 Not applicable Thailand 
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image บูเบิน Euflavine (0.1 G/100G) + Thymol (0.005 G/100G) Ointment Topical บริษัท เอเชี่ยนยูเนี่ยนแล็บบอราตอรี่ จำกัด จำกัด 1988-12-28 Not applicable Thailand
Categories
- ATC Codes
- D08AA03 — Euflavine
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as acridines. These are organic compounds containing the acridine moiety, a linear tricyclic heterocycle which consists of two benzene rings joined by a pyridine ring.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Quinolines and derivatives
- Sub Class
- Benzoquinolines
- Direct Parent
- Acridines
- Alternative Parents
- Aminoquinolines and derivatives / Pyridinium derivatives / Benzenoids / Heteroaromatic compounds / Azacyclic compounds / Primary amines / Organopnictogen compounds / Organic chloride salts / Hydrocarbon derivatives
- Substituents
- Acridine / Amine / Aminoquinoline / Aromatic heteropolycyclic compound / Azacycle / Benzenoid / Heteroaromatic compound / Hydrocarbon derivative / Organic chloride salt / Organic nitrogen compound
- Molecular Framework
- Aromatic heteropolycyclic compounds
- External Descriptors
- organic chloride salt (CHEBI:383703)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 1TW3Q60E36
- CAS number
- 86-40-8
- InChI Key
- KKAJSJJFBSOMGS-UHFFFAOYSA-N
- InChI
- InChI=1S/C14H13N3.ClH/c1-17-13-7-11(15)4-2-9(13)6-10-3-5-12(16)8-14(10)17;/h2-8H,1H3,(H3,15,16);1H
- IUPAC Name
- 3,6-diamino-10-methylacridin-10-ium chloride
- SMILES
- [Cl-].C[N+]1=C2C=C(N)C=CC2=CC2=C1C=C(N)C=C2
References
- General References
- FDA Thailand Product Information: Flavinol (euflavine/thymol) for topical use [Link]
- External Links
- ChemSpider
- 6581
- ChEBI
- 383703
- ChEMBL
- CHEMBL354349
- Wikipedia
- Euflavine
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Ointment Topical Cream 0.1 %w/w - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.00207 mg/mL ALOGPS logP -1.8 ALOGPS logP -2.8 Chemaxon logS -5.1 ALOGPS pKa (Strongest Basic) 2.35 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 55.92 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 72.11 m3·mol-1 Chemaxon Polarizability 25.45 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS splash10-0a4i-0590000000-e59ed1acc5f78655e36b - Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 153.30061 predictedDeepCCS 1.0 (2019) [M+H]+ 155.69633 predictedDeepCCS 1.0 (2019) [M+Na]+ 161.60887 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:39 / Updated at June 02, 2021 20:04