Lofepramine

DB13411ExperimentalSmall molecule

Lofepramine: Overview.

Mechanism: Pharmacologically active on Tryptophan 2,3-dioxygenase
Curator reviewed
Formula / weight: C₂₆H₂₇ClN₂O · 418.97 g/mol (avg)

Resolves to

Compound

Clinical / RWD

Structure

InChIKeySAPNXPWPAUFAJU-UHFFFAOYSA-NSMILESCN(CCCN1C2=CC=CC=C2CCC2=CC=CC=C12)CC(=O)C1=CC=C(Cl)C=C1

Targets

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1,354Drug interactionsStructured to mechanism, not free text

2Marketed productsAcross 1 country and 1 labeller

1ATC codeIncluding every combination product, plus 14 drug categories

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Lofepramine, and which of those have an active Phase 3 trial?

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