Fenyramidol
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Fenyramidol is a muscle relaxant indicated in the symptomatic treatment of musculoskeletal pain and spasms.
- Generic Name
- Fenyramidol
- DrugBank Accession Number
- DB13414
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 214.268
Monoisotopic: 214.110613079 - Chemical Formula
- C13H14N2O
- Synonyms
- Feniramidol
- Fenyramidol
- Fenyramidolum
- Phenyramidol
- External IDs
- IN 511
- MJ 505
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Symptomatic treatment of Pain •••••••••••• - Contraindications & Blackbox Warnings
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your software1,2-Benzodiazepine The risk or severity of CNS depression can be increased when 1,2-Benzodiazepine is combined with Fenyramidol. Acetazolamide The risk or severity of CNS depression can be increased when Acetazolamide is combined with Fenyramidol. Acetophenazine The risk or severity of CNS depression can be increased when Acetophenazine is combined with Fenyramidol. Agomelatine The risk or severity of CNS depression can be increased when Agomelatine is combined with Fenyramidol. Alfentanil The risk or severity of CNS depression can be increased when Alfentanil is combined with Fenyramidol. - Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Product Ingredients
Ingredient UNII CAS InChI Key Phenyramidol hydrochloride M574V6XQH7 326-43-2 HYYDHUILGLWOOP-UHFFFAOYSA-N
Categories
- ATC Codes
- M03BX30 — Fenyramidol
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as aminopyridines and derivatives. These are organic heterocyclic compounds containing an amino group attached to a pyridine ring.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Pyridines and derivatives
- Sub Class
- Aminopyridines and derivatives
- Direct Parent
- Aminopyridines and derivatives
- Alternative Parents
- Secondary alkylarylamines / Imidolactams / Benzene and substituted derivatives / Heteroaromatic compounds / Secondary alcohols / Azacyclic compounds / Organopnictogen compounds / Hydrocarbon derivatives / Aromatic alcohols
- Substituents
- Alcohol / Amine / Aminopyridine / Aromatic alcohol / Aromatic heteromonocyclic compound / Azacycle / Benzenoid / Heteroaromatic compound / Hydrocarbon derivative / Imidolactam
- Molecular Framework
- Aromatic heteromonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- R3V02WL7O3
- CAS number
- 553-69-5
- InChI Key
- ZEAJXCPGHPJVNP-UHFFFAOYSA-N
- InChI
- InChI=1S/C13H14N2O/c16-12(11-6-2-1-3-7-11)10-15-13-8-4-5-9-14-13/h1-9,12,16H,10H2,(H,14,15)
- IUPAC Name
- 1-phenyl-2-[(pyridin-2-yl)amino]ethan-1-ol
- SMILES
- OC(CNC1=NC=CC=C1)C1=CC=CC=C1
References
- General References
- External Links
- ChemSpider
- 9098
- BindingDB
- 235694
- ChEBI
- 134888
- ChEMBL
- CHEMBL1697767
- Wikipedia
- Fenyramidol
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tablet, coated Oral 400 mg Tablet, film coated Oral 400 mg Injection Intramuscular 800 mg/3ml Injection, solution Intramuscular 800 mg/3ml - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.94 mg/mL ALOGPS logP 2.01 ALOGPS logP 1.92 Chemaxon logS -2.4 ALOGPS pKa (Strongest Acidic) 14.1 Chemaxon pKa (Strongest Basic) 6.61 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 45.15 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 64.98 m3·mol-1 Chemaxon Polarizability 23.69 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 144.18793 predictedDeepCCS 1.0 (2019) [M+H]+ 146.58348 predictedDeepCCS 1.0 (2019) [M+Na]+ 152.81543 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:41 / Updated at June 02, 2021 20:04