Pentetrazol

DB13415ApprovedWithdrawnSmall molecule

Pentetrazol is a cough suppressant. Pentetrazol, also known as pentylenetetrazole, is a gamma-aminobutyric acid type A (GABAA) receptor antagonist that was approved by the FDA until 1982.

Mechanism: Pharmacologically active on GABA(A) Receptor
Curator reviewed
Formula / weight: C₆H₁₀N₄ · 138.174 g/mol (avg)
Also known as: Pentylenetetrazol

Resolves to

Compound

UNIIWM5Z385K7TCAS54-95-5ChEMBLCHEMBL116943ChEBI34910KEGGC13692

Clinical / RWD

RxNorm8015ATCR07AB03ATCR07AB53

Structure

InChIKeyCWRVKFFCRWGWCS-UHFFFAOYSA-NSMILESC1CCN2N=NN=C2CC1

What you can answer from here — as of July 10, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

1Structured indicationCondition, population, route and combination as fields, not prose

10ContraindicationsEach with its own population and attribute set

1Marketed productAcross 1 country and 1 labeller

2ATC codesIncluding every combination product, plus 8 drug categories

6+ReferencesStructured and connected to the statements they support

Which other approved drugs treat the same conditions as Pentetrazol, and which companies have late-stage candidates in those indications?

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