Sulbutiamine

DB13416InvestigationalSmall molecule

Sulbutiamine is a thiamine derivative indicated in the treatment of asthenia. It is highly lipophilic, allowing it to cross the blood-brain barrier more easily than other thiamine derivatives.

Chemical structure of Sulbutiamine
Formula / weight
C32H46N8O6S2 · 702.89 g/mol (avg)

Resolves to

Compound
UNII42NCM1BW43CAS3286-46-2ChEMBLCHEMBL1874002ChEBI31290PubChem3002120KEGGC12750
Clinical / RWD
RxNorm37317ATCA11DA02
Structure
InChIKeyCKHJPWQVLKHBIH-GPAWKIAZSA-NSMILESCC(C)C(=O)OCC\C(SS\C(CCOC(=O)C(C)C)=C(/C)N(CC1=C(N)N=C(C)N=C1)C=O)=C(\C)N(CC1=C(N)N=C(C)N=C1)C=O

What you can answer from here — as of March 06, 2025

1Clinical trialPhase, status and sponsor resolved per trial
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1Structured indicationCondition, population, route and combination as fields, not prose
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1ContraindicationEach with its own population and attribute set
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14Marketed productsAcross 6 countries and 10 labellers
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1ATC codeIncluding every combination product, plus 6 drug categories
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4+ReferencesStructured and connected to the statements they support
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Which other approved drugs treat the same conditions as Sulbutiamine, and which companies have late-stage candidates in those indications?

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