Cyclopenthiazide

DB13532ApprovedSmall molecule

Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients... It is a positive allosteric modulator at AMPA-A receptors.

Formula / weight: C₁₃H₁₈ClN₃O₄S₂ · 379.87 g/mol (avg)

Resolves to

Compound

UNIIVX4S2N85F5CAS742-20-1ChEMBLCHEMBL1373254ChEBI91686PubChem2904

Clinical / RWD

RxNorm3000ATCC03AA07ATCC03AB07ATCC03EA07

Structure

InChIKeyBKYKPTRYDKTTJY-UHFFFAOYSA-NSMILESNS(=O)(=O)C1=CC2=C(NC(CC3CCCC3)NS2(=O)=O)C=C1Cl

What you can answer from here — as of July 30, 2026

1,657Drug interactionsStructured to mechanism, not free text

4ATC codesIncluding every combination product, plus 16 drug categories

4+ReferencesStructured and connected to the statements they support

Which companies are running trials of Cyclopenthiazide, in which indications and phases, and which of those programs are still active?

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