This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Ethenzamide
DrugBank Accession Number
DB13544
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 165.192
Monoisotopic: 165.078978598
Chemical Formula
C9H11NO2
Synonyms
  • Etenzamida
  • Etenzamide
  • Ethbenzamide
  • éthenzamide
  • Ethenzamide
  • Ethenzamidum
  • o-Ethoxybenzamide
External IDs
  • J3.352I
  • NSC-28787

Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbacavirEthenzamide may decrease the excretion rate of Abacavir which could result in a higher serum level.
AbciximabThe risk or severity of bleeding and hemorrhage can be increased when Ethenzamide is combined with Abciximab.
AcebutololEthenzamide may decrease the antihypertensive activities of Acebutolol.
AceclofenacThe risk or severity of adverse effects can be increased when Aceclofenac is combined with Ethenzamide.
AcemetacinThe risk or severity of adverse effects can be increased when Ethenzamide is combined with Acemetacin.
AcenocoumarolThe risk or severity of bleeding and hemorrhage can be increased when Ethenzamide is combined with Acenocoumarol.
AcetohexamideThe protein binding of Acetohexamide can be decreased when combined with Ethenzamide.
Acetylsalicylic acidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ethenzamide.
AclidiniumEthenzamide may decrease the excretion rate of Aclidinium which could result in a higher serum level.
AcrivastineEthenzamide may decrease the excretion rate of Acrivastine which could result in a higher serum level.
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Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Penzal QEthenzamide (200 mg/1) + Acetaminophen (300 mg/1) + Caffeine (50 mg/1)TabletOralOASIS TRADING2018-11-20Not applicableUS flag

Categories

ATC Codes
N02BA07 — EthenzamideN02BA77 — Ethenzamide, combinations with psycholepticsN02BA57 — Ethenzamide, combinations excl. psycholeptics
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as benzamides. These are organic compounds containing a carboxamido substituent attached to a benzene ring.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Benzoic acids and derivatives
Direct Parent
Benzamides
Alternative Parents
Phenoxy compounds / Phenol ethers / Benzoyl derivatives / Alkyl aryl ethers / Primary carboxylic acid amides / Organopnictogen compounds / Organonitrogen compounds / Organic oxides / Hydrocarbon derivatives
Substituents
Alkyl aryl ether / Aromatic homomonocyclic compound / Benzamide / Benzoyl / Carboxamide group / Carboxylic acid derivative / Ether / Hydrocarbon derivative / Organic nitrogen compound / Organic oxide
Molecular Framework
Aromatic homomonocyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
L929ZCK4BF
CAS number
938-73-8
InChI Key
SBNKFTQSBPKMBZ-UHFFFAOYSA-N
InChI
InChI=1S/C9H11NO2/c1-2-12-8-6-4-3-5-7(8)9(10)11/h3-6H,2H2,1H3,(H2,10,11)
IUPAC Name
2-ethoxybenzamide
SMILES
CCOC1=C(C=CC=C1)C(N)=O

References

General References
Not Available
KEGG Drug
D01466
ChemSpider
3167
RxNav
24468
ChEBI
31564
ChEMBL
CHEMBL1483877
ZINC
ZINC000000001384
Wikipedia
Ethenzamide

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
TabletOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility2.44 mg/mLALOGPS
logP1.23ALOGPS
logP1.02ChemAxon
logS-1.8ALOGPS
pKa (Strongest Acidic)13.68ChemAxon
pKa (Strongest Basic)-0.93ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area52.32 Å2ChemAxon
Rotatable Bond Count3ChemAxon
Refractivity46.35 m3·mol-1ChemAxon
Polarizability17.29 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
GC-MS Spectrum - EI-BGC-MSsplash10-00di-1900000000-bcc16f34f2d38dc44482
GC-MS Spectrum - EI-BGC-MSsplash10-00dl-6900000000-8e77edbc0a9e88098d92
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created at June 23, 2017 20:44 / Updated at September 28, 2021 21:54