This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Sulfamazone
- DrugBank Accession Number
- DB13556
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Sulfamazone (DB13556)
- Weight
- Average: 560.6
Monoisotopic: 560.114789485 - Chemical Formula
- C23H24N6O7S2
- Synonyms
- Sulfamazone
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Sulfamazone. Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Sulfamazone. Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Sulfamazone. Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfamazone. Benzylpenicillin Sulfamazone may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level. - Food Interactions
- Not Available
Products
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Categories
- ATC Codes
- J01ED09 — Sulfamazone
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as phenylpyrazoles. These are compounds containing a phenylpyrazole skeleton, which consists of a pyrazole bound to a phenyl group.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Azoles
- Sub Class
- Pyrazoles
- Direct Parent
- Phenylpyrazoles
- Alternative Parents
- Benzenesulfonamides / Benzenesulfonyl compounds / Phenylalkylamines / Alkyl aryl ethers / Secondary alkylarylamines / Pyridazines and derivatives / Pyrazolones / Organosulfonamides / Imidolactams / Alkanesulfonic acids show 9 more
- Substituents
- Alkanesulfonic acid / Alkyl aryl ether / Amine / Aminosulfonyl compound / Aromatic heteromonocyclic compound / Azacycle / Benzenesulfonamide / Benzenesulfonyl group / Benzenoid / Ether show 24 more
- Molecular Framework
- Aromatic heteromonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- D7B8U8VA9J
- CAS number
- 65761-24-2
- InChI Key
- BGLHAKAJGYLSOX-UHFFFAOYSA-N
- InChI
- InChI=1S/C23H24N6O7S2/c1-15-21(23(30)29(28(15)2)17-7-5-4-6-8-17)22(38(33,34)35)24-16-9-11-18(12-10-16)37(31,32)27-19-13-14-20(36-3)26-25-19/h4-14,22,24H,1-3H3,(H,25,27)(H,33,34,35)
- IUPAC Name
- (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)({4-[(6-methoxypyridazin-3-yl)sulfamoyl]phenyl}amino)methanesulfonic acid
- SMILES
- COC1=CC=C(NS(=O)(=O)C2=CC=C(NC(C3=C(C)N(C)N(C3=O)C3=CC=CC=C3)S(O)(=O)=O)C=C2)N=N1
References
- General References
- Not Available
- External Links
- ChemSpider
- 163211
- ChEBI
- 131763
- ChEMBL
- CHEMBL2104921
- Wikipedia
- Sulfamazone
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Suppository Tablet - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0389 mg/mL ALOGPS logP 1.61 ALOGPS logP -0.16 Chemaxon logS -4.2 ALOGPS pKa (Strongest Acidic) -1.6 Chemaxon pKa (Strongest Basic) -0.6 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 11 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 171.13 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 141.93 m3·mol-1 Chemaxon Polarizability 54.34 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 213.36993 predictedDeepCCS 1.0 (2019) [M+H]+ 215.76552 predictedDeepCCS 1.0 (2019) [M+Na]+ 221.6045 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:44 / Updated at February 21, 2021 18:54