Acefylline

DB13573ExperimentalSmall molecule

Acefylline: Overview.

Mechanism: Pharmacologically active on cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 3',5'-cyclic-AMP phosphodiesterase 4A, and 3',5'-cyclic-AMP phosphodiesterase 4D
Curator reviewed
Formula / weight: C₉H₁₀N₄O₄ · 238.203 g/mol (avg)
Code names: NSC-52996

Resolves to

Compound

UNIIM494UE2YEPCAS652-37-9ChEMBLCHEMBL70246ChEBI94615

Clinical / RWD

ATCR03DA09

Structure

InChIKeyHCYFGRCYSCXKNQ-UHFFFAOYSA-NSMILESCN1C2=C(N(CC(O)=O)C=N2)C(=O)N(C)C1=O

Targets

Q9Y233PDE10AP27815PDE4AQ08499PDE4DQ9ULC6PADI1Q9ULW8PADI3

What you can answer from here — as of August 30, 2026

5Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

607Drug interactionsStructured to mechanism, not free text

1ATC codeIncluding every combination product, plus 8 drug categories

11+ReferencesStructured and connected to the statements they support

Which drugs share a target with Acefylline, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Log In Paid Account Log In