This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Succinylsulfathiazole
- DrugBank Accession Number
- DB13580
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Succinylsulfathiazole (DB13580)
- Weight
- Average: 355.38
Monoisotopic: 355.029662879 - Chemical Formula
- C13H13N3O5S2
- Synonyms
- Succinylsulfathiazole
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Succinylsulfathiazole. Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Succinylsulfathiazole. Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Succinylsulfathiazole. Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Succinylsulfathiazole. Benzylpenicillin Succinylsulfathiazole may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level. - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image แบคซีลา เม็ด Succinylsulfathiazole (250 mg) + Diiodohydroxyquinoline (250 mg) + Furazolidone (50 mg) + Neomycin sulfate (50 mg) Tablet บริษัท ไบร์วู๊ดฟาร์มาซูติคอล จำกัด 1986-03-07 2020-07-19 Thailand 
Categories
- ATC Codes
- A07AB04 — Succinylsulfathiazole
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as benzenesulfonamides. These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring.
- Kingdom
- Organic compounds
- Super Class
- Benzenoids
- Class
- Benzene and substituted derivatives
- Sub Class
- Benzenesulfonamides
- Direct Parent
- Benzenesulfonamides
- Alternative Parents
- Anilides / Benzenesulfonyl compounds / N-arylamides / Organosulfonamides / Fatty amides / Thiazoles / Aminosulfonyl compounds / Heteroaromatic compounds / Secondary carboxylic acid amides / Monocarboxylic acids and derivatives show 6 more
- Substituents
- Aminosulfonyl compound / Anilide / Aromatic heteromonocyclic compound / Azacycle / Azole / Benzenesulfonamide / Benzenesulfonyl group / Carbonyl group / Carboxamide group / Carboxylic acid show 21 more
- Molecular Framework
- Aromatic heteromonocyclic compounds
- External Descriptors
- 1,3-thiazole (CHEBI:9309)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- RSS8647O4S
- CAS number
- 116-43-8
- InChI Key
- SKVLYVHULOWXTD-UHFFFAOYSA-N
- InChI
- InChI=1S/C13H13N3O5S2/c17-11(5-6-12(18)19)15-9-1-3-10(4-2-9)23(20,21)16-13-14-7-8-22-13/h1-4,7-8H,5-6H2,(H,14,16)(H,15,17)(H,18,19)
- IUPAC Name
- 3-({4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}carbamoyl)propanoic acid
- SMILES
- OC(=O)CCC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC1=NC=CS1
References
- General References
- Not Available
- External Links
- KEGG Compound
- C11745
- ChemSpider
- 5124
- BindingDB
- 50238667
- 37289
- ChEBI
- 9309
- ChEMBL
- CHEMBL1484857
- ZINC
- ZINC000001532343
- Wikipedia
- Succinylsulfathiazole
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tablet - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.185 mg/mL ALOGPS logP 0.99 ALOGPS logP 0.87 Chemaxon logS -3.3 ALOGPS pKa (Strongest Acidic) 3.36 Chemaxon pKa (Strongest Basic) 0.59 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 125.46 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 83.33 m3·mol-1 Chemaxon Polarizability 33.41 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 196.0078336 predictedDarkChem Lite v0.1.0 [M-H]- 169.21407 predictedDeepCCS 1.0 (2019) [M+H]+ 195.7988336 predictedDarkChem Lite v0.1.0 [M+H]+ 171.57204 predictedDeepCCS 1.0 (2019) [M+Na]+ 178.28322 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:44 / Updated at February 21, 2021 18:54