This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Moroxydine
- DrugBank Accession Number
- DB13597
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Moroxydine (DB13597)
- Weight
- Average: 171.204
Monoisotopic: 171.112010059 - Chemical Formula
- C6H13N5O
- Synonyms
- Moroxidina
- Moroxydine
- Moroxydinum
- External IDs
- SKF 8898-A
- SKF 8898A
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAdenovirus type 7 vaccine live The therapeutic efficacy of Adenovirus type 7 vaccine live can be decreased when used in combination with Moroxydine. Anthrax vaccine The therapeutic efficacy of Anthrax vaccine can be decreased when used in combination with Moroxydine. Bacillus calmette-guerin substrain connaught live antigen The therapeutic efficacy of Bacillus calmette-guerin substrain connaught live antigen can be decreased when used in combination with Moroxydine. Bacillus calmette-guerin substrain russian BCG-I live antigen The therapeutic efficacy of Bacillus calmette-guerin substrain russian BCG-I live antigen can be decreased when used in combination with Moroxydine. Bacillus calmette-guerin substrain tice live antigen The therapeutic efficacy of Bacillus calmette-guerin substrain tice live antigen can be decreased when used in combination with Moroxydine. - Food Interactions
- Not Available
Categories
- ATC Codes
- J05AX01 — Moroxydine
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as biguanides. These are organic compounds containing two N-linked guanidines.
- Kingdom
- Organic compounds
- Super Class
- Organic nitrogen compounds
- Class
- Organonitrogen compounds
- Sub Class
- Guanidines
- Direct Parent
- Biguanides
- Alternative Parents
- Morpholines / Oxacyclic compounds / Dialkyl ethers / Carboximidamides / Azacyclic compounds / Organopnictogen compounds / Imines / Hydrocarbon derivatives
- Substituents
- Aliphatic heteromonocyclic compound / Azacycle / Biguanide / Carboximidamide / Dialkyl ether / Ether / Hydrocarbon derivative / Imine / Morpholine / Organic oxygen compound
- Molecular Framework
- Aliphatic heteromonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- O611591WAH
- CAS number
- 3731-59-7
- InChI Key
- KJHOZAZQWVKILO-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H13N5O/c7-5(8)10-6(9)11-1-3-12-4-2-11/h1-4H2,(H5,7,8,9,10)
- IUPAC Name
- N-(morpholine-4-carboximidoyl)guanidine
- SMILES
- NC(=N)NC(=N)N1CCOCC1
References
- General References
- Not Available
- External Links
- ChemSpider
- 64715
- BindingDB
- 50227841
- 30227
- ChEBI
- 94665
- ChEMBL
- CHEMBL1490434
- ZINC
- ZINC000009302211
- Wikipedia
- Moroxydine
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 1.41 mg/mL ALOGPS logP -1.5 ALOGPS logP -1.1 Chemaxon logS -2.1 ALOGPS pKa (Strongest Acidic) 19.16 Chemaxon pKa (Strongest Basic) 11.85 Chemaxon Physiological Charge 2 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 98.22 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 65.72 m3·mol-1 Chemaxon Polarizability 17.22 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 139.0594 predictedDeepCCS 1.0 (2019) [M+H]+ 141.97069 predictedDeepCCS 1.0 (2019) [M+Na]+ 151.04759 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:45 / Updated at February 21, 2021 18:54