Moroxydine
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Moroxydine
- DrugBank Accession Number
- DB13597
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 171.204
Monoisotopic: 171.112010059 - Chemical Formula
- C6H13N5O
- Synonyms
- Moroxidina
- Moroxydine
- Moroxydinum
- External IDs
- SKF 8898-A
- SKF 8898A
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAdenovirus type 7 vaccine live The therapeutic efficacy of Adenovirus type 7 vaccine live can be decreased when used in combination with Moroxydine. Anthrax vaccine The therapeutic efficacy of Anthrax vaccine can be decreased when used in combination with Moroxydine. Bacillus calmette-guerin substrain connaught live antigen The therapeutic efficacy of Bacillus calmette-guerin substrain connaught live antigen can be decreased when used in combination with Moroxydine. Bacillus calmette-guerin substrain russian BCG-I live antigen The therapeutic efficacy of Bacillus calmette-guerin substrain russian BCG-I live antigen can be decreased when used in combination with Moroxydine. Bacillus calmette-guerin substrain tice live antigen The therapeutic efficacy of Bacillus calmette-guerin substrain tice live antigen can be decreased when used in combination with Moroxydine. BCG vaccine The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Moroxydine. Human adenovirus e serotype 4 strain cl-68578 antigen The therapeutic efficacy of Human adenovirus e serotype 4 strain cl-68578 antigen can be decreased when used in combination with Moroxydine. Rubella virus vaccine The therapeutic efficacy of Rubella virus vaccine can be decreased when used in combination with Moroxydine. Typhoid Vaccine Live The therapeutic efficacy of Typhoid Vaccine Live can be decreased when used in combination with Moroxydine. Varicella zoster vaccine (live/attenuated) The therapeutic efficacy of Varicella zoster vaccine (live/attenuated) can be decreased when used in combination with Moroxydine. Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Categories
- ATC Codes
- J05AX01 — Moroxydine
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as biguanides. These are organic compounds containing two N-linked guanidines.
- Kingdom
- Organic compounds
- Super Class
- Organic nitrogen compounds
- Class
- Organonitrogen compounds
- Sub Class
- Guanidines
- Direct Parent
- Biguanides
- Alternative Parents
- Morpholines / Oxacyclic compounds / Dialkyl ethers / Carboximidamides / Azacyclic compounds / Organopnictogen compounds / Imines / Hydrocarbon derivatives
- Substituents
- Aliphatic heteromonocyclic compound / Azacycle / Biguanide / Carboximidamide / Dialkyl ether / Ether / Hydrocarbon derivative / Imine / Morpholine / Organic oxygen compound
- Molecular Framework
- Aliphatic heteromonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- O611591WAH
- CAS number
- 3731-59-7
- InChI Key
- KJHOZAZQWVKILO-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H13N5O/c7-5(8)10-6(9)11-1-3-12-4-2-11/h1-4H2,(H5,7,8,9,10)
- IUPAC Name
- N-(morpholine-4-carboximidoyl)guanidine
- SMILES
- NC(=N)NC(=N)N1CCOCC1
References
- General References
- Not Available
- External Links
- ChemSpider
- 64715
- BindingDB
- 50227841
- 30227
- ChEBI
- 94665
- ChEMBL
- CHEMBL1490434
- ZINC
- ZINC000009302211
- Wikipedia
- Moroxydine
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 1.41 mg/mL ALOGPS logP -1.5 ALOGPS logP -1.1 Chemaxon logS -2.1 ALOGPS pKa (Strongest Acidic) 19.16 Chemaxon pKa (Strongest Basic) 11.85 Chemaxon Physiological Charge 2 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 98.22 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 65.72 m3·mol-1 Chemaxon Polarizability 17.22 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS Not Available Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available LC-MS/MS Spectrum - LC-ESI-QTOF , positive LC-MS/MS splash10-00di-0900000000-004f60fe21c1349c00bc LC-MS/MS Spectrum - LC-ESI-QTOF , positive LC-MS/MS splash10-03di-0900000000-6f3ad90ed45ff0426cb3 LC-MS/MS Spectrum - LC-ESI-QTOF , positive LC-MS/MS splash10-03di-0900000000-af624a42fcd18dce6156
Drug created at June 23, 2017 20:45 / Updated at February 21, 2021 18:54