Selenium (75Se) norcholesterol
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Summary
Selenium (75Se) norcholesterol is a radiopharmaceutical indicated in nuclear imaging studies of the digestive system.
- Generic Name
- Selenium (75Se) norcholesterol
- DrugBank Accession Number
- DB13622
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 475.614
Monoisotopic: 475.293039737 - Chemical Formula
- C28H48OSe
- Synonyms
- Selenium se-75 norcholesterol
- External IDs
- J40.704F
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareEltrombopag The bioavailability of Selenium (75Se) norcholesterol can be decreased when combined with Eltrombopag. - Food Interactions
- Not Available
Products
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Categories
- ATC Codes
- V09XX03 — Selenium (75se) norcholesterol
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- XWR21TJ99H
- CAS number
- 63795-61-9
- InChI Key
- AEVGUKVBCBHBNF-MJMUOCKJSA-N
- InChI
- InChI=1S/C28H48OSe/c1-18(2)7-6-8-19(3)26-11-12-27-25-15-20(17-30-5)24-16-21(29)9-10-22(24)23(25)13-14-28(26,27)4/h18-21,23,25-27,29H,6-17H2,1-5H3/t19-,20+,21+,23-,25-,26-,27+,28-/m1/s1/i30-4
- IUPAC Name
- (1S,5S,8R,10S,11S,14R,15R)-15-methyl-8-{[methyl(⁷⁵Se)selanyl]methyl}-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-2(7)-en-5-ol
- SMILES
- C[75Se]C[C@@H]1C[C@H]2[C@@H]3CC[C@H]([C@H](C)CCCC(C)C)[C@@]3(C)CC[C@@H]2C2=C1C[C@@H](O)CC2
References
- General References
- AIFA: Sehcat (Selenium 75Se Norcholesterol) Oral Capsule [Link]
- External Links
- ChemSpider
- 108863
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Capsule Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.000337 mg/mL ALOGPS logP 6.4 ALOGPS logP 6.31 Chemaxon logS -6.2 ALOGPS pKa (Strongest Acidic) 18.19 Chemaxon pKa (Strongest Basic) -1.4 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 20.23 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 138.28 m3·mol-1 Chemaxon Polarizability 54.58 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule Yes Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 213.64436 predictedDeepCCS 1.0 (2019) [M+H]+ 215.89665 predictedDeepCCS 1.0 (2019) [M+Na]+ 221.72762 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:45 / Updated at May 29, 2021 18:12