Pridinol

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Pridinol is an atropine-like muscle relaxant indicated in the treatment of muscle pain associated with muscle tightness.

Generic Name
Pridinol
DrugBank Accession Number
DB13642
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 295.426
Monoisotopic: 295.193614429
Chemical Formula
C20H25NO
Synonyms
  • Pridinol

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
1,2-BenzodiazepineThe risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Pridinol.
AcetazolamideThe risk or severity of adverse effects can be increased when Acetazolamide is combined with Pridinol.
AcetophenazineThe risk or severity of adverse effects can be increased when Acetophenazine is combined with Pridinol.
AclidiniumPridinol may increase the central nervous system depressant (CNS depressant) activities of Aclidinium.
AgomelatineThe risk or severity of adverse effects can be increased when Agomelatine is combined with Pridinol.
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Pridinol.
AlimemazineThe risk or severity of adverse effects can be increased when Alimemazine is combined with Pridinol.
AlmotriptanThe risk or severity of adverse effects can be increased when Almotriptan is combined with Pridinol.
AlosetronThe risk or severity of adverse effects can be increased when Alosetron is combined with Pridinol.
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with Pridinol.
Interactions
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Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Pridinol mesilateAQ4K0AJT6G6856-31-1VNJHUUNVDMYCRH-UHFFFAOYSA-N

Categories

ATC Codes
M03BX03 — Pridinol
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Diphenylmethanes
Direct Parent
Diphenylmethanes
Alternative Parents
Aralkylamines / Piperidines / Tertiary alcohols / 1,3-aminoalcohols / Trialkylamines / Azacyclic compounds / Organopnictogen compounds / Hydrocarbon derivatives / Aromatic alcohols
Substituents
1,3-aminoalcohol / Alcohol / Amine / Aralkylamine / Aromatic alcohol / Aromatic heteromonocyclic compound / Azacycle / Diphenylmethane / Hydrocarbon derivative / Organic nitrogen compound
Molecular Framework
Aromatic heteromonocyclic compounds
External Descriptors
piperidines, tertiary alcohol (CHEBI:75247)
Affected organisms
Not Available

Chemical Identifiers

UNII
9E75Q6SUUB
CAS number
511-45-5
InChI Key
RQXCLMGKHJWMOA-UHFFFAOYSA-N
InChI
InChI=1S/C20H25NO/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21/h1-2,4-7,10-13,22H,3,8-9,14-17H2
IUPAC Name
1,1-diphenyl-3-(piperidin-1-yl)propan-1-ol
SMILES
OC(CCN1CCCCC1)(C1=CC=CC=C1)C1=CC=CC=C1

References

General References
  1. AIFA Product Information: Lyseen (pridinol) for oral use [Link]
ChemSpider
4735
RxNav
34479
ChEBI
75247
ChEMBL
CHEMBL404215
ZINC
ZINC000001482149
Wikipedia
Pridinol

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solutionIntramuscular; Intravenous
Suppository
TabletOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0192 mg/mLALOGPS
logP3.69ALOGPS
logP3.7ChemAxon
logS-4.2ALOGPS
pKa (Strongest Acidic)13.36ChemAxon
pKa (Strongest Basic)9.34ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area23.47 Å2ChemAxon
Rotatable Bond Count5ChemAxon
Refractivity92.27 m3·mol-1ChemAxon
Polarizability34.68 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created on June 23, 2017 20:45 / Updated on May 29, 2021 18:12