Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Sodium tartrate
- DrugBank Accession Number
- DB13707
- Background
Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals. It is obtained as a byproduct of wine manufacturing. Sodium tartrate is generally recognized as safe (GRAS) as a direct human food ingredient. It acts as an emulsifier and pH control agent in food products 1.
This compound is commonly used as an emulsifier in cheese/cheese spread products and is not to exceed 4% concentration, according to Health Canada regulations 5.
- Type
- Small Molecule
- Groups
- Approved
- Structure
Structure for Sodium tartrate (DB13707)
- Weight
- Average: 194.05
Monoisotopic: 193.98032641 - Chemical Formula
- C4H4Na2O6
- Synonyms
- Bisodium tartrate
- Disodium L-(+)-tartrate
- disodium tartrate
- sodium L-tartrate
- Tartaric acid, disodium salt
- External IDs
- E-335(II)
- INS NO.335(II)
- INS-335(II)
Pharmacology
- Indication
It acts as an emulsifier and pH control agent in food products 1, 9. In the laboratory, it is used while performing the Karl Fischer equation, which is used to determine the water content of various substances 10, 1.
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
Sodium tartrate is a white, crystalline powder, used as an emulsifier and a binding agent. It can be used in jellies, cheeses, sausage casings and any foods which contain fats or oils 8.
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Abdominal cramps, nausea, and vomiting 2.
Oral LD50 in rats is 4360 mg kg-1 3.
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcetazolamide The risk or severity of dehydration can be increased when Acetazolamide is combined with Sodium tartrate. Aclidinium The therapeutic efficacy of Sodium tartrate can be decreased when used in combination with Aclidinium. Alfentanil The therapeutic efficacy of Sodium tartrate can be decreased when used in combination with Alfentanil. Alloin The risk or severity of adverse effects can be increased when Sodium tartrate is combined with Alloin. Almasilate The therapeutic efficacy of Sodium tartrate can be decreased when used in combination with Almasilate. - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Limonade Rodeca Liquid 5.6 g / 100 mL Oral Rodeca Inc., Division Of Technilab Inc. 1962-12-31 2003-09-22 Canada 
Categories
- ATC Codes
- A06AD21 — Sodium tartrate
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as beta hydroxy acids and derivatives. These are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom.
- Kingdom
- Organic compounds
- Super Class
- Organic acids and derivatives
- Class
- Hydroxy acids and derivatives
- Sub Class
- Beta hydroxy acids and derivatives
- Direct Parent
- Beta hydroxy acids and derivatives
- Alternative Parents
- Short-chain hydroxy acids and derivatives / Monosaccharides / Fatty acids and conjugates / Dicarboxylic acids and derivatives / Secondary alcohols / Carboxylic acid salts / 1,2-diols / Carboxylic acids / Organic sodium salts / Organic oxides show 2 more
- Substituents
- 1,2-diol / Alcohol / Aliphatic acyclic compound / Beta-hydroxy acid / Carbonyl group / Carboxylic acid / Carboxylic acid derivative / Carboxylic acid salt / Dicarboxylic acid or derivatives / Fatty acid show 10 more
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- organic sodium salt (CHEBI:63017)
- Affected organisms
- Humans and other mammals
Chemical Identifiers
- UNII
- QTO9JB4MDD
- CAS number
- 868-18-8
- InChI Key
- HELHAJAZNSDZJO-OLXYHTOASA-L
- InChI
- InChI=1S/C4H6O6.2Na/c5-1(3(7)8)2(6)4(9)10;;/h1-2,5-6H,(H,7,8)(H,9,10);;/q;2*+1/p-2/t1-,2-;;/m1../s1
- IUPAC Name
- disodium (2R,3R)-2,3-dihydroxybutanedioate
- SMILES
- [Na+].[Na+].O[C@H]([C@@H](O)C([O-])=O)C([O-])=O
References
- General References
- Sodium Tartrate, PubChem [Link]
- Sodium Tartrate Monograph [Link]
- Sodium tartrate, chemspider [Link]
- Sodium Tartrate Overiew, Science Direct [Link]
- List of Permitted Emulsifying, Gelling, Stabilizing or Thickening Agents (Lists of Permitted Food Additives) [Link]
- The pharmacology of sodium tartrate [Link]
- Sodium tartrate [Link]
- Sodium Tartrate, FCC [Link]
- Tartrates [Link]
- KARL FISCHER ELECTROMETRIC TITRATION METHOD FOR DETERMINATION OF WATER CONTENT [File]
- External Links
- PubChem Compound
- 162637
- PubChem Substance
- 347829311
- ChemSpider
- 142788
- 56524
- ChEBI
- 63017
- ChEMBL
- CHEMBL2107781
- Wikipedia
- Sodium_tartrate
- MSDS
- Download (47.1 KB)
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Liquid Oral 5.6 g / 100 mL - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
Property Value Source melting point (°C) 120 MSDS water solubility Soluble in cold water MSDS - Predicted Properties
Property Value Source Water Solubility 779.0 mg/mL ALOGPS logP -1.9 ALOGPS logP -1.8 Chemaxon logS 0.6 ALOGPS pKa (Strongest Acidic) 2.72 Chemaxon pKa (Strongest Basic) -4.3 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 120.72 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 47.89 m3·mol-1 Chemaxon Polarizability 10.83 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS splash10-0gb9-9200000000-477d3386816182e4b2fc - Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 127.4025803 predictedDarkChem Lite v0.1.0 [M-H]- 126.84835 predictedDeepCCS 1.0 (2019) [M+H]+ 132.1495803 predictedDarkChem Lite v0.1.0 [M+H]+ 129.03746 predictedDeepCCS 1.0 (2019) [M+Na]+ 127.4625803 predictedDarkChem Lite v0.1.0 [M+Na]+ 134.94759 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:47 / Updated at June 12, 2020 16:53