Potassium guaiacolsulfonate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Potassium guaiacolsulfonate is a mucolytic and expectorant indicated to relieve a productive cough.

Generic Name
Potassium guaiacolsulfonate
DrugBank Accession Number
DB13735
Background

Guaiacolsulfonate is an aromatic sulfonic acid. Potassium guaiacolsulfonate salt is an expectorant that thins the mucus in the lungs and reduces chest congestion.

Type
Small Molecule
Groups
Experimental
Synonyms
  • Guaiacolsulfonate potassium
  • Potassium sulfoguaiacolate

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Associated Therapies
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AcebutololPotassium guaiacolsulfonate may increase the hyperkalemic activities of Acebutolol.
AceclofenacPotassium guaiacolsulfonate may increase the hyperkalemic activities of Aceclofenac.
AcemetacinPotassium guaiacolsulfonate may increase the hyperkalemic activities of Acemetacin.
Acetylsalicylic acidPotassium guaiacolsulfonate may increase the hyperkalemic activities of Acetylsalicylic acid.
AlclofenacPotassium guaiacolsulfonate may increase the hyperkalemic activities of Alclofenac.
AliskirenPotassium guaiacolsulfonate may increase the hyperkalemic activities of Aliskiren.
AmilorideThe risk or severity of hyperkalemia can be increased when Potassium guaiacolsulfonate is combined with Amiloride.
AminophenazonePotassium guaiacolsulfonate may increase the hyperkalemic activities of Aminophenazone.
AmiodaronePotassium guaiacolsulfonate may increase the hyperkalemic activities of Amiodarone.
AmlodipinePotassium guaiacolsulfonate may increase the hyperkalemic activities of Amlodipine.
Interactions
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Food Interactions
Not Available

Products

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Active Moieties
NameKindUNIICASInChI Key
Potassium cationionic295O53K15224203-36-9NPYPAHLBTDXSSS-UHFFFAOYSA-N
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
ANTIBEKSIN SURUP, 100 MLPotassium guaiacolsulfonate (175 mg/5ml) + Ephedrine hydrochloride (5 mg/5ml) + Pheniramine maleate (15 mg/5ml) + Sodium citrate (65 mg/5ml)SyrupOralYAVUZ İLAÇ ECZA DEPOSU MEDİKAL ÜRÜNLER SAN.VE TİC. A.Ş.2020-08-14Not applicableTurkey flag
ARTU 100 ML SURUPPotassium guaiacolsulfonate (175 mg/5ml) + Sodium benzoate (5 mg/5ml) + Ephedrine hydrochloride (5 mg/5ml) + Promethazine hydrochloride (5 mg/5ml)SyrupOralGÜNSA GÜNEY İLAÇ VE HAMMADDELER SAN. VE TİC. A.Ş.2020-08-14Not applicableTurkey flag
GAYABEN 150 ML SURUPPotassium guaiacolsulfonate (133.3 mg) + Diphenhydramine hydrochloride (10 mg) + Guaifenesin (100 mg) + Pentoxyverine citrate (8.3 mg)SyrupOralBİLİM İLAÇ SAN. VE TİC. A.Ş.2020-08-14Not applicableTurkey flag
ดูทรอส เอ็กซ์Potassium guaiacolsulfonate (200 mg/5mL) + Bromhexine hydrochloride (4 mg/5mL)Syrupบริษัท ไทยนครพัฒนา จำกัด2013-02-06Not applicableThailand flag
ทอไกลโคโล่Potassium guaiacolsulfonate (200 mg/5mL) + Bromhexine hydrochloride (2 mg/5mL)Syrupบริษัท สยามเภสัช จำกัด1985-09-17Not applicableThailand flag
บรอมโซ เอ็กซ์เป็คทอแรนท์Potassium guaiacolsulfonate (200 MG/5ML) + Bromhexine hydrochloride (4 MG/5ML)Syrupบริษัท ที.โอ.เคมีคอลส์ (1979) จำกัด1999-05-202019-10-21Thailand flag
ยาเม็ดเคลือบ ซีเดตัสPotassium guaiacolsulfonate (100 MG) + Chlorpheniramine maleate (2 MG) + Dextromethorphan hydrobromide (15 MG)Tablet, sugar coatedOralบริษัท อังกฤษตรางู (แอล.พี.) จำกัด2013-04-24Not applicableThailand flag
ยาแก้ไอน้ำเชื่อมเด็กแอลพีตราเสือดาวPotassium guaiacolsulfonate (100 MG/5ML) + Sodium citrate (100 MG/5ML)Syrupบริษัท ห้างขายยาตราเสือดาว จำกัด2012-12-17Not applicableThailand flag
ยาแก้ไอเด็ก (ตรางู)Potassium guaiacolsulfonate (12.5 MG/5ML) + Ammonium chloride (75 MG/5ML) + Chlorpheniramine maleate (0.25 MG/5ML)Syrupบริษัท อังกฤษตรางู (แอล.พี.) จำกัด1986-07-04Not applicableThailand flag
ยาแก้ไอเด็กตราธงPotassium guaiacolsulfonate (12.5 MG/5ML) + Ammonium chloride (75 MG/5ML) + Chlorpheniramine (0.25 MG/5ML)Syrupบริษัท เอเชี่ยนยูเนี่ยนแล็บบอราตอรี่ จำกัด จำกัด1988-05-17Not applicableThailand flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
P-TussPotassium guaiacolsulfonate (300 mg/5mL) + Hydrocodone bitartrate (5 mg/5mL)LiquidOralPrasco, Laboratories2010-12-012011-01-21US flag
Phenylephrine Carbetapentane Potassium GuaiacolsulfonatePotassium guaiacolsulfonate (100 mg/5mL) + Pentoxyverine (20 mg/5mL) + Phenylephrine (10 mg/5mL)LiquidOralRiver's Edge Pharmaceuticals, LLC2010-03-012010-11-20US flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
21A795TNZD
CAS number
1321-14-8

References

General References
  1. AIFA Package Leaflet: CORYFIN SEDATIVO FLUIDIFICANTE (dextromethorphan and potassium guaiacolsulfonate) oral syrup [Link]
PubChem Substance
347911449
RxNav
91275
Wikipedia
Guaiacolsulfonate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Suspension
Solution / dropsBuccal
LiquidOral
SyrupOral
Syrup
Tablet, sugar coatedOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on June 23, 2017 20:47 / Updated on May 22, 2021 06:01