This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Potassium guaiacolsulfonate is a mucolytic and expectorant indicated to relieve a productive cough.
- Generic Name
- Potassium guaiacolsulfonate
- DrugBank Accession Number
- DB13735
- Background
Guaiacolsulfonate is an aromatic sulfonic acid. Potassium guaiacolsulfonate salt is an expectorant that thins the mucus in the lungs and reduces chest congestion.
- Type
- Small Molecule
- Groups
- Experimental
- Synonyms
- Guaiacolsulfonate potassium
- Potassium sulfoguaiacolate
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
- Associated Therapies
- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcebutolol Potassium guaiacolsulfonate may increase the hyperkalemic activities of Acebutolol. Aceclofenac Potassium guaiacolsulfonate may increase the hyperkalemic activities of Aceclofenac. Acemetacin Potassium guaiacolsulfonate may increase the hyperkalemic activities of Acemetacin. Acetylsalicylic acid Potassium guaiacolsulfonate may increase the hyperkalemic activities of Acetylsalicylic acid. Alclofenac Potassium guaiacolsulfonate may increase the hyperkalemic activities of Alclofenac. Aliskiren Potassium guaiacolsulfonate may increase the hyperkalemic activities of Aliskiren. Amiloride The risk or severity of hyperkalemia can be increased when Potassium guaiacolsulfonate is combined with Amiloride. Aminophenazone Potassium guaiacolsulfonate may increase the hyperkalemic activities of Aminophenazone. Amiodarone Potassium guaiacolsulfonate may increase the hyperkalemic activities of Amiodarone. Amlodipine Potassium guaiacolsulfonate may increase the hyperkalemic activities of Amlodipine. 
Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Active Moieties
Name Kind UNII CAS InChI Key Potassium cation ionic 295O53K152 24203-36-9 NPYPAHLBTDXSSS-UHFFFAOYSA-N - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ANTIBEKSIN SURUP, 100 ML Potassium guaiacolsulfonate (175 mg/5ml) + Ephedrine hydrochloride (5 mg/5ml) + Pheniramine maleate (15 mg/5ml) + Sodium citrate (65 mg/5ml) Syrup Oral YAVUZ İLAÇ ECZA DEPOSU MEDİKAL ÜRÜNLER SAN.VE TİC. A.Ş. 2020-08-14 Not applicable Turkey 
ARTU 100 ML SURUP Potassium guaiacolsulfonate (175 mg/5ml) + Sodium benzoate (5 mg/5ml) + Ephedrine hydrochloride (5 mg/5ml) + Promethazine hydrochloride (5 mg/5ml) Syrup Oral GÜNSA GÜNEY İLAÇ VE HAMMADDELER SAN. VE TİC. A.Ş. 2020-08-14 Not applicable Turkey GAYABEN 150 ML SURUP Potassium guaiacolsulfonate (133.3 mg) + Diphenhydramine hydrochloride (10 mg) + Guaifenesin (100 mg) + Pentoxyverine citrate (8.3 mg) Syrup Oral BİLİM İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 Not applicable Turkey ดูทรอส เอ็กซ์ Potassium guaiacolsulfonate (200 mg/5mL) + Bromhexine hydrochloride (4 mg/5mL) Syrup บริษัท ไทยนครพัฒนา จำกัด 2013-02-06 Not applicable Thailand 
ทอไกลโคโล่ Potassium guaiacolsulfonate (200 mg/5mL) + Bromhexine hydrochloride (2 mg/5mL) Syrup บริษัท สยามเภสัช จำกัด 1985-09-17 Not applicable Thailand บรอมโซ เอ็กซ์เป็คทอแรนท์ Potassium guaiacolsulfonate (200 MG/5ML) + Bromhexine hydrochloride (4 MG/5ML) Syrup บริษัท ที.โอ.เคมีคอลส์ (1979) จำกัด 1999-05-20 2019-10-21 Thailand ยาเม็ดเคลือบ ซีเดตัส Potassium guaiacolsulfonate (100 MG) + Chlorpheniramine maleate (2 MG) + Dextromethorphan hydrobromide (15 MG) Tablet, sugar coated Oral บริษัท อังกฤษตรางู (แอล.พี.) จำกัด 2013-04-24 Not applicable Thailand ยาแก้ไอน้ำเชื่อมเด็กแอลพีตราเสือดาว Potassium guaiacolsulfonate (100 MG/5ML) + Sodium citrate (100 MG/5ML) Syrup บริษัท ห้างขายยาตราเสือดาว จำกัด 2012-12-17 Not applicable Thailand ยาแก้ไอเด็ก (ตรางู) Potassium guaiacolsulfonate (12.5 MG/5ML) + Ammonium chloride (75 MG/5ML) + Chlorpheniramine maleate (0.25 MG/5ML) Syrup บริษัท อังกฤษตรางู (แอล.พี.) จำกัด 1986-07-04 Not applicable Thailand ยาแก้ไอเด็กตราธง Potassium guaiacolsulfonate (12.5 MG/5ML) + Ammonium chloride (75 MG/5ML) + Chlorpheniramine (0.25 MG/5ML) Syrup บริษัท เอเชี่ยนยูเนี่ยนแล็บบอราตอรี่ จำกัด จำกัด 1988-05-17 Not applicable Thailand - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image P-Tuss Potassium guaiacolsulfonate (300 mg/5mL) + Hydrocodone bitartrate (5 mg/5mL) Liquid Oral Prasco, Laboratories 2010-12-01 2011-01-21 US 
Phenylephrine Carbetapentane Potassium Guaiacolsulfonate Potassium guaiacolsulfonate (100 mg/5mL) + Pentoxyverine (20 mg/5mL) + Phenylephrine (10 mg/5mL) Liquid Oral River's Edge Pharmaceuticals, LLC 2010-03-01 2010-11-20 US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 21A795TNZD
- CAS number
- 1321-14-8
References
- General References
- AIFA Package Leaflet: CORYFIN SEDATIVO FLUIDIFICANTE (dextromethorphan and potassium guaiacolsulfonate) oral syrup [Link]
- External Links
- PubChem Substance
- 347911449
- 91275
- Wikipedia
- Guaiacolsulfonate
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Suspension Solution / drops Buccal Liquid Oral Syrup Oral Syrup Tablet, sugar coated Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
- Not Available
- Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at June 23, 2017 20:47 / Updated at May 22, 2021 06:01