Identification

Summary

Cat dander extract is an extract from Cat dander extract used in allergy testing.

Generic Name
Cat dander extract
DrugBank Accession Number
DB13904
Background

Cat dander extract is either subcutaneously or intracutaneously administered and contains dry cat dander or dry defatted cat pelt. It is used in the diagnosis and treatment (immunotherapy) of patients with a history of allergy to cats. An allergic reaction to cats is induced by the presence of antigen-specific IgE antibodies that are bound to specific receptors on mast cells and basophils. The allergy diagnostic process involves assessing allergy history, clinical evaluation, and skin test reactivity. Cat dander extract can be used in immunotherapy in individuals who cannot avoid exposure to cat allergens to initiate hyposensitization.

Type
Biotech
Groups
Approved
Biologic Classification
Allergenics
Allergen Extract
Synonyms
  • Cat dander diagnostic allergen extract
  • Felis catus dander

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Standardized Cat Hair ApSolution10000 unit/1Intradermal; SubcutaneousJubilant Hollisterstier Llc1998-08-28Not applicableCanada flag
Standardized Cat PeltInjection, solution10000 [BAU]/1mLPercutaneous; SubcutaneousJubilant Hollisterstier Llc1992-10-20Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Standardized Cat Hair Allergenic ExtractCat dander extract (5000 [BAU]/1mL) + Felis catus skin (5000 [BAU]/1mL)SolutionIntradermal; Percutaneous; SubcutaneousGreer Laboratories, Inc.1992-09-24Not applicableUS flag
Standardized Cat Hair Allergenic ExtractCat dander extract (10000 [BAU]/1mL) + Felis catus skin (10000 [BAU]/1mL)SolutionIntradermal; Percutaneous; SubcutaneousGreer Laboratories, Inc.1992-09-24Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
ZDN2AC0L08
CAS number
Not Available

References

General References
  1. Morales M, Gallego M, Iraola V, Taules M, de Oliveira E, Moya R, Carnes J: In vitro evidence of efficacy and safety of a polymerized cat dander extract for allergen immunotherapy. BMC Immunol. 2017 Feb 24;18(1):10. doi: 10.1186/s12865-017-0193-0. [Article]
  2. Alvarez-Cuesta E, Berges-Gimeno P, Gonzalez-Mancebo E, Fernandez-Caldas E, Cuesta-Herranz J, Casanovas M: Sublingual immunotherapy with a standardized cat dander extract: evaluation of efficacy in a double blind placebo controlled study. Allergy. 2007 Jul;62(7):810-7. [Article]
PubChem Substance
347911473
RxNav
465953

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedTreatmentAllergic Reaction1
0TerminatedTreatmentCat Allergy (Disorder)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionIntradermal; Percutaneous; Subcutaneous
SolutionIntradermal; Subcutaneous10000 unit/1
Injection, solutionPercutaneous; Subcutaneous10000 [BAU]/1mL
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at September 08, 2017 20:22 / Updated at May 15, 2022 15:58