This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Thiosalicylic acid
- DrugBank Accession Number
- DB14026
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 154.186
Monoisotopic: 154.008850126 - Chemical Formula
- C7H6O2S
- Synonyms
- 2-Carboxythiophenol
- 2-Mercaptobenzoic acid
- 2-Sulfanylbenzoic acid
- 2-Thiosalicylic acid
- o-Benzoic acid thiol
- o-Carboxythiophenol
- o-Mercaptobenzoic acid
- o-Mercaptobenzösäure
- o-Sulfhydrylbenzoic acid
- o-Thiosalicylic acid
- Thiophenol-2-carboxylic acid
- Thiosalicylate
- Thiosalicylic acid
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAbciximab The risk or severity of bleeding can be increased when Thiosalicylic acid is combined with Abciximab. Acarbose Thiosalicylic acid may increase the hypoglycemic activities of Acarbose. Aceclofenac The therapeutic efficacy of Thiosalicylic acid can be decreased when used in combination with Aceclofenac. Acenocoumarol Thiosalicylic acid may increase the anticoagulant activities of Acenocoumarol. Acetaminophen The risk or severity of adverse effects can be increased when Acetaminophen is combined with Thiosalicylic acid. Acetazolamide The risk or severity of adverse effects can be increased when Thiosalicylic acid is combined with Acetazolamide. Acetohexamide Thiosalicylic acid may increase the hypoglycemic activities of Acetohexamide. Acetyldigitoxin The serum concentration of Acetyldigitoxin can be decreased when it is combined with Thiosalicylic acid. Acetylsalicylic acid The therapeutic efficacy of Thiosalicylic acid can be decreased when used in combination with Acetylsalicylic acid. Albiglutide Thiosalicylic acid may increase the hypoglycemic activities of Albiglutide. Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- International/Other Brands
- Pirosal / Thiocyl
Categories
- Drug Categories
- Acids, Carbocyclic
- Alkylmercury Compounds
- Analgesics
- Analgesics, Non-Narcotic
- Benzene Derivatives
- Benzoates
- Central Nervous System Agents
- Ethylmercury Compounds
- Hydroxy Acids
- Hydroxybenzoates
- Organomercury Compounds
- Organometallic Compounds
- Peripheral Nervous System Agents
- Phenols
- Salicylates
- Sensory System Agents
- Sulfur Compounds
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- CIP6LXN5XW
- CAS number
- 147-93-3
- InChI Key
- NBOMNTLFRHMDEZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C7H6O2S/c8-7(9)5-3-1-2-4-6(5)10/h1-4,10H,(H,8,9)
- IUPAC Name
- 2-sulfanylbenzoic acid
- SMILES
- OC(=O)C1=C(S)C=CC=C1
References
- General References
- Not Available
- External Links
- KEGG Drug
- D08586
- ChemSpider
- 5248
- BindingDB
- 50239391
- 322165
- ChEBI
- 59124
- ChEMBL
- CHEMBL119888
- ZINC
- ZINC000000284503
- PDBe Ligand
- JKE
- Wikipedia
- Thiosalicylic_acid
- PDB Entries
- 3lk1 / 4e4a / 6g9x / 6k4t
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 1.7 mg/mL ALOGPS logP 1.65 ALOGPS logP 1.72 Chemaxon logS -2 ALOGPS pKa (Strongest Acidic) 3.34 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 37.3 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 41.32 m3·mol-1 Chemaxon Polarizability 14.89 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created at May 15, 2018 16:51 / Updated at February 21, 2021 18:54