Hydroxybutyloxide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Hydroxybutyloxide
DrugBank Accession Number
DB14079
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 162.229
Monoisotopic: 162.12559444
Chemical Formula
C8H18O3
Synonyms
  • 4,4'-Oxydi-2-butanol
  • bis(3-hydroxybutyl) ether
  • Colenormol
  • Dihydroxydibutylether
  • Diskin
  • Dyskinebyl

Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
GaleoLiquid5 g/50mLOralCho-A Pharm.Co.,Ltd.2017-02-28Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
GaleoHydroxybutyloxide (5 g/50mL)LiquidOralCho-A Pharm.Co.,Ltd.2017-02-28Not applicableUS flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
CR6X2Y7NRR
CAS number
821-33-0
InChI Key
AFSYRVDDZGJTIL-UHFFFAOYSA-N
InChI
InChI=1S/C8H18O3/c1-7(9)3-5-11-6-4-8(2)10/h7-10H,3-6H2,1-2H3
IUPAC Name
4-(3-hydroxybutoxy)butan-2-ol
SMILES
CC(O)CCOCCC(C)O

References

General References
Not Available
ChemSpider
83187
RxNav
14699
ChEBI
134793

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedTreatmentDyspepsia1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LiquidOral5 g/50mL
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility112.0 mg/mLALOGPS
logP0.23ALOGPS
logP-0.3Chemaxon
logS-0.16ALOGPS
pKa (Strongest Acidic)15.29Chemaxon
pKa (Strongest Basic)-2.5Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area49.69 Å2Chemaxon
Rotatable Bond Count6Chemaxon
Refractivity44.17 m3·mol-1Chemaxon
Polarizability19.07 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-05fr-9400000000-9634db5d0ae5b4fa0e4d
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-000i-9000000000-6cad220ed0ca4b34e383
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-05fr-9000000000-def40c9390c28d7a0db7
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-00du-9000000000-9fd91671ee015876cf90
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-05fs-9000000000-b52f1247bdf80cb4d52c
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-052f-9000000000-b12bb592c79232909ecc
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at June 17, 2018 18:41 / Updated at June 12, 2020 16:53