Sacubitrilat

DB14127ExperimentalSmall moleculeNeprilysin Inhibitor

A metabolite of LCZ696 with neprilysin inhibitory activity.

Chemical structure of Sacubitrilat
Formula / weight
C22H25NO5 · 383.444 g/mol (avg)
Code names
LBQ-657

Resolves to

Compound
UNIISPI5PBF81SCAS149709-44-4ChEMBLCHEMBL417007
Clinical / RWD
RxNorm1860608
Structure
InChIKeyDOBNVUFHFMVMDB-BEFAXECRSA-NSMILESC[C@H](C[C@@H](CC1=CC=C(C=C1)C1=CC=CC=C1)NC(=O)CCC(O)=O)C(O)=O
Targets
P08473MME

What you can answer from here — as of January 29, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
1+ReferenceStructured and connected to the statements they support
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