This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Methyl salicylate 2-ethylbutyrate
DrugBank Accession Number
DB14130
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 250.294
Monoisotopic: 250.12050906
Chemical Formula
C14H18O4
Synonyms
  • Methyl diethylacetylsalicylate
  • Salicylic acid, methyl ester, 2-ethylbutyrate

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug events
Improve clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events & improve clinical decision support.
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
Learn more
Improve decision support & research outcomes with our structured adverse effects data.
Learn more
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Thera DermMethyl salicylate 2-ethylbutyrate (28 mg/240mg) + 7-Aminodesacetoxycephalosporanic acid (450 mg/240mg) + Camphor leaf oil (6 mg/240mg) + Menthol (13 mg/240mg) + Peppermint oil (13 mg/240mg)LotionTopicalManna Omni International Incorporated2017-10-31Not applicableUS flag
Thera Derm Roll OnMethyl salicylate 2-ethylbutyrate (18 mg/90mg) + (-)-menthol 1-propylene glycol carbonate (9 mg/90mg) + Camphor (4 mg/90mg) + Peppermint oil (9 mg/90mg)LiquidTopicalManna Omni International Incorporated2017-07-31Not applicableUS flag
TheraDermMethyl salicylate 2-ethylbutyrate (24 mg/120mg) + Camphor (5 mg/120mg) + Menthol (12 mg/120mg) + Peppermint oil (12 mg/120mg)SprayTopicalManna Omni International Incorporated2017-03-17Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Thera DermMethyl salicylate 2-ethylbutyrate (28 mg/240mg) + 7-Aminodesacetoxycephalosporanic acid (450 mg/240mg) + Camphor leaf oil (6 mg/240mg) + Menthol (13 mg/240mg) + Peppermint oil (13 mg/240mg)LotionTopicalManna Omni International Incorporated2017-10-31Not applicableUS flag
Thera Derm Roll OnMethyl salicylate 2-ethylbutyrate (18 mg/90mg) + (-)-menthol 1-propylene glycol carbonate (9 mg/90mg) + Camphor (4 mg/90mg) + Peppermint oil (9 mg/90mg)LiquidTopicalManna Omni International Incorporated2017-07-31Not applicableUS flag
TheraDermMethyl salicylate 2-ethylbutyrate (24 mg/120mg) + Camphor (5 mg/120mg) + Menthol (12 mg/120mg) + Peppermint oil (12 mg/120mg)SprayTopicalManna Omni International Incorporated2017-03-17Not applicableUS flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
J8D9175Q0G
CAS number
85005-92-1
InChI Key
QXNXIPALJCPMNY-UHFFFAOYSA-N
InChI
InChI=1S/C14H18O4/c1-4-10(5-2)13(15)18-12-9-7-6-8-11(12)14(16)17-3/h6-10H,4-5H2,1-3H3
IUPAC Name
methyl 2-[(2-ethylbutanoyl)oxy]benzoate
SMILES
CCC(CC)C(=O)OC1=CC=CC=C1C(=O)OC

References

General References
Not Available
ChemSpider
731086
RxNav
1921110
ZINC
ZINC000000363950

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
Not AvailableCompletedTreatmentHypopituitarism1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LotionTopical
LiquidTopical
SprayTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0547 mg/mLALOGPS
logP3.43ALOGPS
logP3.72Chemaxon
logS-3.7ALOGPS
pKa (Strongest Basic)-6.8Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area52.6 Å2Chemaxon
Rotatable Bond Count7Chemaxon
Refractivity67.62 m3·mol-1Chemaxon
Polarizability26.83 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at June 26, 2018 13:24 / Updated at June 12, 2020 16:53