This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
p-Aminophenol
DrugBank Accession Number
DB14144
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 109.1259
Monoisotopic: 109.052763851
Chemical Formula
C6H7NO
Synonyms
  • 4-Aminobenzenol
  • 4-Aminophenol
  • 4-Hydroxyaniline
  • p-hydroxyaniline

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Improve decision support & research outcomes with our structured adverse effects data.
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
p-Aminophenol hydrochlorideIWL2N22RFY51-78-5RVGOBWDGAVAVPJ-UHFFFAOYSA-N
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Beautiful Womans Hair Loves Colorful Bubbles Hair Dye 5n Natural BrownLiquid0.01 mg/1mLTopicalModlina Cosmetics Co., Ltd2013-08-12Not applicableUS flag
SALON CODE Glam BrownLiquid0.34 g/100mLTopicalDaolcosmetic Co.,ltd2018-09-042018-09-10US flag
SALON CODE Glam CacaoLiquid0.44 g/100mLTopicalDaolcosmetic Co.,ltd2018-09-042018-09-10US flag
SALON CODE Glam Rose GoldLiquid0.8 g/100mLTopicalDaolcosmetic Co.,ltd2018-09-042018-09-10US flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
SALON CODE Glam Hair Color Glam Brownp-Aminophenol (0.34 g/100mL) + Hydrogen peroxide (5.845 g/100mL)KitTopicalDaolcosmetic Co.,ltd2018-09-04Not applicableUS flag
SALON CODE Glam Hair Color Glam Cacaop-Aminophenol (0.44 g/100mL) + Hydrogen peroxide (5.845 g/100mL)KitTopicalDaolcosmetic Co.,ltd2018-09-04Not applicableUS flag
SALON CODE Glam Hair Color Glam Rose Goldp-Aminophenol (0.8 g/100mL) + Hydrogen peroxide (5.845 g/100mL)KitTopicalDaolcosmetic Co.,ltd2018-09-04Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Beautiful Womans Hair Loves Colorful Bubbles Hair Dye 5n Natural Brownp-Aminophenol (0.01 mg/1mL)LiquidTopicalModlina Cosmetics Co., Ltd2013-08-12Not applicableUS flag
SALON CODE Glam Brownp-Aminophenol (0.34 g/100mL)LiquidTopicalDaolcosmetic Co.,ltd2018-09-042018-09-10US flag
SALON CODE Glam Cacaop-Aminophenol (0.44 g/100mL)LiquidTopicalDaolcosmetic Co.,ltd2018-09-042018-09-10US flag
SALON CODE Glam Hair Color Glam Brownp-Aminophenol (0.34 g/100mL) + Hydrogen peroxide (5.845 g/100mL)KitTopicalDaolcosmetic Co.,ltd2018-09-04Not applicableUS flag
SALON CODE Glam Hair Color Glam Cacaop-Aminophenol (0.44 g/100mL) + Hydrogen peroxide (5.845 g/100mL)KitTopicalDaolcosmetic Co.,ltd2018-09-04Not applicableUS flag
SALON CODE Glam Hair Color Glam Rose Goldp-Aminophenol (0.8 g/100mL) + Hydrogen peroxide (5.845 g/100mL)KitTopicalDaolcosmetic Co.,ltd2018-09-04Not applicableUS flag
SALON CODE Glam Rose Goldp-Aminophenol (0.8 g/100mL)LiquidTopicalDaolcosmetic Co.,ltd2018-09-042018-09-10US flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
R7P8FRP05V
CAS number
123-30-8
InChI Key
PLIKAWJENQZMHA-UHFFFAOYSA-N
InChI
InChI=1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
IUPAC Name
4-aminophenol
SMILES
NC1=CC=C(O)C=C1

References

General References
Not Available
Human Metabolome Database
HMDB0001169
KEGG Compound
C02372
ChemSpider
392
BindingDB
26195
RxNav
1435279
ChEBI
17602
ChEMBL
CHEMBL1142
ZINC
ZINC000004623758
PDBe Ligand
4NL
Wikipedia
4-Aminophenol
PDB Entries
2orl

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LiquidTopical0.01 mg/1mL
LiquidTopical0.34 g/100mL
LiquidTopical0.44 g/100mL
KitTopical
LiquidTopical0.8 g/100mL
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility121.0 mg/mLALOGPS
logP0.47ALOGPS
logP0.84ChemAxon
logS0.04ALOGPS
pKa (Strongest Acidic)10.4ChemAxon
pKa (Strongest Basic)5.43ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area46.25 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity32.74 m3·mol-1ChemAxon
Polarizability11.23 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
GC-MS Spectrum - EI-BGC-MSsplash10-0a4i-6900000000-9c5bfea7a6ff3c845001
GC-MS Spectrum - EI-BGC-MSsplash10-0pe9-9300000000-8ff47e2157f6fbfe6754
GC-MS Spectrum - GC-EI-TOFGC-MSsplash10-0f79-1890000000-c8247060f46131c693d1
GC-MS Spectrum - GC-EI-TOFGC-MSsplash10-03di-1927000000-b873199d9ac85605a4df
Mass Spectrum (Electron Ionization)MSsplash10-0a4i-9700000000-00bffb48fd955696bccc
MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)LC-MS/MSsplash10-03di-3900000000-906f96b14dfdad2310de
MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)LC-MS/MSsplash10-014i-9000000000-d56be0077647bc66e962
MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)LC-MS/MSsplash10-014i-9000000000-937794addf5b73c988e9
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-03di-2900000000-1d20b6ad92e8fe4dcb55
1H NMR Spectrum1D NMRNot Applicable
1H NMR Spectrum1D NMRNot Applicable
13C NMR Spectrum1D NMRNot Applicable
[1H,13C] 2D NMR Spectrum2D NMRNot Applicable

Drug created at June 27, 2018 20:07 / Updated at June 12, 2020 16:53