p-Aminophenol

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name

p-Aminophenol

DrugBank Accession Number

DB14144

Background

Not Available

Type

Small Molecule

Groups

Experimental

Structure

Similar Structures

Weight: Average: 109.1259
Monoisotopic: 109.052763851
Chemical Formula: C₆H₇NO

Synonyms

4-Aminobenzenol
4-Aminophenol
4-Hydroxyaniline
p-hydroxyaniline

Pharmacology

Indication: Not Available
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Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available
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Toxicity: Not Available
Pathways: Not Available
Pharmacogenomic Effects/ADRs: Not Available

Interactions

Drug Interactions: This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions: Not Available

Products

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Product Ingredients

Ingredient	UNII	CAS	InChI Key
p-Aminophenol hydrochloride	IWL2N22RFY	51-78-5	RVGOBWDGAVAVPJ-UHFFFAOYSA-N

Over the Counter Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End
Beautiful Womans Hair Loves Colorful Bubbles Hair Dye 5n Natural Brown	Liquid	0.01 mg/1mL	Topical	Modlina Cosmetics Co., Ltd	2013-08-12	Not applicable
SALON CODE Glam Brown	Liquid	0.34 g/100mL	Topical	Daolcosmetic Co.,ltd	2018-09-04	2018-09-10
SALON CODE Glam Cacao	Liquid	0.44 g/100mL	Topical	Daolcosmetic Co.,ltd	2018-09-04	2018-09-10
SALON CODE Glam Rose Gold	Liquid	0.8 g/100mL	Topical	Daolcosmetic Co.,ltd	2018-09-04	2018-09-10

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
SALON CODE Glam Hair Color Glam Brown	p-Aminophenol (0.34 g/100mL) + Hydrogen peroxide (5.845 g/100mL)	Kit	Topical	Daolcosmetic Co.,ltd	2018-09-04	Not applicable
SALON CODE Glam Hair Color Glam Cacao	p-Aminophenol (0.44 g/100mL) + Hydrogen peroxide (5.845 g/100mL)	Kit	Topical	Daolcosmetic Co.,ltd	2018-09-04	Not applicable
SALON CODE Glam Hair Color Glam Rose Gold	p-Aminophenol (0.8 g/100mL) + Hydrogen peroxide (5.845 g/100mL)	Kit	Topical	Daolcosmetic Co.,ltd	2018-09-04	Not applicable

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
Beautiful Womans Hair Loves Colorful Bubbles Hair Dye 5n Natural Brown	p-Aminophenol (0.01 mg/1mL)	Liquid	Topical	Modlina Cosmetics Co., Ltd	2013-08-12	Not applicable
SALON CODE Glam Brown	p-Aminophenol (0.34 g/100mL)	Liquid	Topical	Daolcosmetic Co.,ltd	2018-09-04	2018-09-10
SALON CODE Glam Cacao	p-Aminophenol (0.44 g/100mL)	Liquid	Topical	Daolcosmetic Co.,ltd	2018-09-04	2018-09-10
SALON CODE Glam Hair Color Glam Brown	p-Aminophenol (0.34 g/100mL) + Hydrogen peroxide (5.845 g/100mL)	Kit	Topical	Daolcosmetic Co.,ltd	2018-09-04	Not applicable
SALON CODE Glam Hair Color Glam Cacao	p-Aminophenol (0.44 g/100mL) + Hydrogen peroxide (5.845 g/100mL)	Kit	Topical	Daolcosmetic Co.,ltd	2018-09-04	Not applicable
SALON CODE Glam Hair Color Glam Rose Gold	p-Aminophenol (0.8 g/100mL) + Hydrogen peroxide (5.845 g/100mL)	Kit	Topical	Daolcosmetic Co.,ltd	2018-09-04	Not applicable
SALON CODE Glam Rose Gold	p-Aminophenol (0.8 g/100mL)	Liquid	Topical	Daolcosmetic Co.,ltd	2018-09-04	2018-09-10

Chemical Identifiers

UNII: R7P8FRP05V
CAS number: 123-30-8
InChI Key: PLIKAWJENQZMHA-UHFFFAOYSA-N
InChI: InChI=1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
IUPAC Name: 4-aminophenol
SMILES: NC1=CC=C(O)C=C1

References

General References

Not Available

External Links

Human Metabolome Database: HMDB0001169
KEGG Compound: C02372
ChemSpider: 392
BindingDB: 26195
RxNav: 1435279
ChEBI: 17602
ChEMBL: CHEMBL1142
ZINC: ZINC000004623758
PDBe Ligand: 4NL
Wikipedia: 4-Aminophenol

PDB Entries

2orl

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Liquid	Topical	0.01 mg/1mL
Liquid	Topical	0.34 g/100mL
Liquid	Topical	0.44 g/100mL
Kit	Topical
Liquid	Topical	0.8 g/100mL

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
Water Solubility	121.0 mg/mL	ALOGPS
logP	0.47	ALOGPS
logP	0.84	ChemAxon
logS	0.04	ALOGPS
pKa (Strongest Acidic)	10.4	ChemAxon
pKa (Strongest Basic)	5.43	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	46.25 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	32.74 m³·mol^-1	ChemAxon
Polarizability	11.23 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	1	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Spectrum	Spectrum Type	Splash Key
Predicted GC-MS Spectrum - GC-MS	Predicted GC-MS	Not Available
GC-MS Spectrum - EI-B	GC-MS	splash10-0a4i-6900000000-9c5bfea7a6ff3c845001
GC-MS Spectrum - EI-B	GC-MS	splash10-0pe9-9300000000-8ff47e2157f6fbfe6754
GC-MS Spectrum - GC-EI-TOF	GC-MS	splash10-0f79-1890000000-c8247060f46131c693d1
GC-MS Spectrum - GC-EI-TOF	GC-MS	splash10-03di-1927000000-b873199d9ac85605a4df
Mass Spectrum (Electron Ionization)	MS	splash10-0a4i-9700000000-00bffb48fd955696bccc
MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)	LC-MS/MS	splash10-03di-3900000000-906f96b14dfdad2310de
MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)	LC-MS/MS	splash10-014i-9000000000-d56be0077647bc66e962
MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)	LC-MS/MS	splash10-014i-9000000000-937794addf5b73c988e9
Predicted MS/MS Spectrum - 10V, Positive (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)	Predicted LC-MS/MS	Not Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)	Predicted LC-MS/MS	Not Available
LC-MS/MS Spectrum - LC-ESI-QFT , positive	LC-MS/MS	splash10-03di-2900000000-1d20b6ad92e8fe4dcb55
1H NMR Spectrum	1D NMR	Not Applicable
1H NMR Spectrum	1D NMR	Not Applicable
13C NMR Spectrum	1D NMR	Not Applicable
[1H,13C] 2D NMR Spectrum	2D NMR	Not Applicable

Drug created at June 27, 2018 20:07 / Updated at June 12, 2020 16:53

p-Aminophenol

Identification

Structure for p-Aminophenol (DB14144)

Pharmacology

Interactions

Products

Categories

Chemical Identifiers

References

Clinical Trials

Pharmacoeconomics

Properties

Spectra