Isoeugenol

DB14188ApprovedSmall moleculeStandardized Chemical Allergen

Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. It is also a significant dermatologic... It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to 200 p.p.m. since 1998 according to guidelines issued by the fragrance industry.

Chemical structure of Isoeugenol
Mechanism
Curator reviewed
Primary indication
Isoeugenol is approved by the FDA for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age...Curator reviewed
Formula / weight
C10H12O2 · 164.204 g/mol (avg)
First approval
United States, 2012
Also known as
4-Propenylguaiacol · Propenylguaiacol

Resolves to

Clinical / RWD
Structure
InChIKeyBJIOGJUNALELMI-UHFFFAOYSA-NSMILESCOC1=CC(C=CC)=CC=C1O

What you can answer from here — as of July 07, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1Marketed productAcross 1 country and 1 labeller
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4+ReferencesStructured and connected to the statements they support
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