N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine

DB14196ApprovedSmall moleculeStandardized Chemical Allergen

N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. It is also a dermatological sensitizer and allergen. Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test.

Chemical structure of N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine
Primary indication
N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.Curator reviewed
Formula / weight
C18H22N2 · 266.388 g/mol (avg)
First approval
United States, 2012
Also known as
CPPD

Resolves to

Clinical / RWD
Structure
InChIKeyZRMMVODKVLXCBB-UHFFFAOYSA-NSMILESC1CCC(CC1)NC1=CC=C(NC2=CC=CC=C2)C=C1

What you can answer from here — as of June 12, 2020

1Marketed productAcross 1 country and 1 labeller
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Which companies are running trials of N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine, in which indications and phases, and which of those programs are still active?

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