Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties. It is found within many commercially available cosmetics, lotions, and makeup removers. It is also... It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area.
- Primary indication
- Methylchloroisothiazolinone is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.Curator reviewed
- Formula / weight
- C4H4ClNOS · 149.59 g/mol (avg)
- First approval
- United States, 2012
Resolves to
Clinical / RWD
Structure
InChIKey
DHNRXBZYEKSXIM-UHFFFAOYSA-NSMILESCN1SC(Cl)=CC1=OWhat you can answer from here — as of April 02, 2025
Which companies are running trials of Methylchloroisothiazolinone, in which indications and phases, and which of those programs are still active?
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