Quaternium-15

DB14198ApprovedSmall moleculeStandardized Chemical Allergen

Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics. It is an anti-microbial agent by virtue of being a formaldehyde releaser, however... It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin.

Chemical structure of Quaternium-15
Primary indication
Quaternium-15 is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.Curator reviewed
Formula / weight
C9H16Cl2N4 · 251.156 g/mol (avg)
First approval
United States, 2012
Also known as
Quaternium 15
Code names
XD-1840

Resolves to

Clinical / RWD
Structure
InChIKeyUKHVLWKBNNSRRR-UHFFFAOYSA-MSMILES[Cl-].[H]C(Cl)=C([H])C[N+]12CN3CN(CN(C3)C1)C2

What you can answer from here — as of March 06, 2025

1Marketed productAcross 1 country and 1 labeller
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2+ReferencesStructured and connected to the statements they support
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Which companies are running trials of Quaternium-15, in which indications and phases, and which of those programs are still active?

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