Influenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) antigen (propiolactone inactivated)

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Influenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) antigen (propiolactone inactivated)
DrugBank Accession Number
DB14459
Background

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". This defence includes the production of humoral immunity through the development of antibodies (through memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus that it was previously exposed to.

There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV). Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques. Live vaccines maintain their replicative ability.

Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Inactivated
Synonyms
Not Available

Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Prophylaxis ofInfluenza a virus infection••••••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Active Moieties
NameKindUNIICASInChI Key
Influenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) hemagglutinin antigen (propiolactone inactivated)hemagglutininC2C4DA5K06Not AvailableNot applicable
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
AfluriaInfluenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/Singapore/GP1908/2015 IVR-180A (H1N1) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza B virus B/Brisbane/46/2015 antigen (propiolactone inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSeqirus S.R.L.2011-07-152017-08-17US flag
AfluriaInfluenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/California/7/2009 X-181 (H1N1) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza B virus B/Brisbane/60/2008 antigen (propiolactone inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSeqirus S.R.L.2011-07-152016-06-17US flag
AfluriaInfluenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/Singapore/GP1908/2015 IVR-180A (H1N1) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza B virus B/Brisbane/46/2015 antigen (propiolactone inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSeqirus S.R.L.2011-07-152017-08-17US flag
AfluriaInfluenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/Singapore/GP1908/2015 IVR-180A (H1N1) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza B virus B/Brisbane/46/2015 antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 BVR-1B antigen (propiolactone inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSeqirus S.R.L.2016-09-282017-08-17US flag
AfluriaInfluenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/California/7/2009 X-181 (H1N1) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza B virus B/Brisbane/60/2008 antigen (propiolactone inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSeqirus S.R.L.2011-07-152016-06-17US flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
3DZY3Q314E
CAS number
Not Available

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
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Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, suspensionIntramuscular
KitTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at July 05, 2018 18:03 / Updated at June 12, 2020 16:53